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| Other names | 4-(diphenylmethoxy)-1-methyl-piperidine |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral,Topical |
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| Pharmacokinetic data | |
| Eliminationhalf-life | 24–40 hours[1] |
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| ECHA InfoCard | 100.005.170 |
| Chemical and physical data | |
| Formula | C19H23NO |
| Molar mass | 281.399 g·mol−1 |
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Diphenylpyraline (DPP; sold asAllergen,Arbid,Belfene,Diafen,Hispril,Histyn,Lergobine,Lyssipol,Mepiben,Neargal) is afirst-generation antihistamine withanticholinergic effects of thediphenylpiperidine class.[2][3][4] It is marketed inEurope for the treatment ofallergies.[2][3][5] DPP has also been found to act as adopamine reuptake inhibitor and produceshyperactivity in rodents.[6] It has been shown to be useful in the treatment ofParkinsonism.[7]

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| DATTooltip Dopamine transporter (DRIsTooltip Dopamine reuptake inhibitors) |
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| NETTooltip Norepinephrine transporter (NRIsTooltip Norepinephrine reuptake inhibitors) |
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| SERTTooltip Serotonin transporter (SRIsTooltip Serotonin reuptake inhibitors) |
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