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| Names | |
|---|---|
| Preferred IUPAC name Diphenylmethanol | |
| Other names Benzhydrol Diphenylcarbinol Hydroxydiphenylmethane | |
| Identifiers | |
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3D model (JSmol) | |
| ChEBI | |
| ChemSpider |
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| ECHA InfoCard | 100.001.849 |
| EC Number |
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| UNII | |
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| Properties | |
| C13H12O | |
| Molar mass | 184.238 g·mol−1 |
| Appearance | White crystals |
| Density | 1.103 g/cm3 |
| Melting point | 69 °C (156 °F; 342 K) |
| Boiling point | 298 °C (568 °F; 571 K) |
| 0.5 g/L (20 °C) | |
| −119.1·10−6 cm3/mol | |
| Hazards[2] | |
| GHS labelling: | |
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| Warning | |
| H315,H319,H335 | |
| P261,P264,P271,P280,P302+P352,P304+P340,P305+P351+P338,P312,P321,P332+P313,P337+P313,P362,P403+P233,P405,P501 | |
| Related compounds | |
Related compounds | Benzophenone |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Diphenylmethanol is theorganic compound with the formula (C6H5)2CHOH. Also known asbenzhydrol, it is a white solid and the parent member of a large class of diaryl alcohols.
Diphenylmethanol may be prepared by aGrignard reaction betweenphenylmagnesium bromide andbenzaldehyde[citation needed]. An alternative method involves reducingbenzophenone withsodium borohydride or withzinc dust or with sodium amalgam and water.[3]
It has uses inperfume andpharmaceutical manufacture. In perfumery it is used as afixative. In pharmaceutical manufacture it is used in thesynthesis ofantihistamines /antiallergenic agents andantihypertensive agents . It is used in the synthesis ofmodafinil[4] and thebenzhydryl group is present in the structure of many histamineH1 antagonists likediphenylhydramine. Benzhydrol is also used in the production ofagrochemicals as well as other organic compounds and as a terminating group inpolymerizations.
Diphenylmethanol is anirritant to the eyes, skin and respiratory system.
