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Dipeptidases areenzymes secreted byenterocytes into thesmall intestine. Dipeptidases hydrolyze bound pairs ofamino acids, calleddipeptides.
Dipeptidases are secreted onto thebrush border of the villi in the small intestine, where they cleave dipeptides into their two component amino acids prior to absorption. They are also found within the enterocytes themselves, performing cytosolic digestion of absorbed dipeptides.
Dipeptidases areexopeptidases, classified underEC number 3.4.13.[1]