In thehuman brain, thediencephalon (orinterbrain[1]) is a division of theforebrain (embryonicprosencephalon). It is situated between thetelencephalon and themidbrain (embryonicmesencephalon). The diencephalon has also been known as thetweenbrain in older literature.[2] It consists of structures that are on either side of thethird ventricle, including thethalamus, thehypothalamus, theepithalamus and thesubthalamus.
Theoptic nerve (CNII) attaches to the diencephalon. The optic nerve is a sensory (afferent) nerve responsible forvision andsight; it runs from the eye through theoptic canal in theskull and attaches to the diencephalon. Theretina itself is derived from theoptic cup, a part of the embryonic diencephalon.[citation needed]
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The diencephalon is the region of the embryonic vertebrateneural tube that gives rise to anteriorforebrain structures including thethalamus,hypothalamus,posterior portion of thepituitary gland, and thepineal gland. The diencephalon encloses a cavity called the third ventricle. The thalamus serves as a relay centre for sensory and motor impulses between the spinal cord and medulla oblongata, and the cerebrum. It recognizes sensory impulses of heat, cold, pain, pressure etc. The floor of the third ventricle is called the hypothalamus. It has control centres for control of eye movement and hearing responses.
Diagram depicting the main subdivisions of the embryonic vertebrate brain. These regions will later differentiate into forebrain, midbrain and hindbrain structures.
Reconstruction of peripheral nerves of a human embryo of 10.2 mm. (Label for Diencephalon is at left.)