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| Formula | C15H17Cl2NO2 |
| Molar mass | 314.21 g·mol−1 |
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Dichloropane ((−)-2β-Carbomethoxy-3β-(3,4-dichlorophenyl)tropane,RTI-111,O-401) is astimulant of thephenyltropane class that acts as aserotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) withIC50 values of 3.13, 18, and 0.79 nM, respectively.[1] In animal studies, dichloropane had a slower onset and longer duration of action compared tococaine.[2][3]
Methylecgonidine is the direct precursor to this compound.[4]
The thermodynamic isomer with a trans -CO2Me group is still active. This isomer was used by Neurosearch to make three different phenyltropanes which were tested in clinical trials.