Irish bioinformatics professor
Desmond Gerard Higgins is aProfessor ofBioinformatics atUniversity College Dublin ,[ 3] [ 12] [ 13] [ 14] CLUSTAL ,[ 15] multiple sequence alignment . According toNature [ 10] [ 11] scientific papers of all time.[ 16] [ 17] [ 18]
Higgins was educated atTrinity College, Dublin [ 19] PhD in 1988 for research onnumerical taxonomy ofPterygote insects .[ 20] [ 21]
Research in the Higgins laboratory[ 3] evolutionary biology . TheCLUSTAL program formultiple sequence alignment has been developed in the Higgins lab and theT-Coffee software was initially developed in the lab with by Cedric Notredame.Multivariate statistics are used to analysemicroarray data sets andmolecular evolution such as the evolution ofpromoters ,introns andnon-coding RNA .[ 12] [ 19]
Higgins was elected aFellow of theInternational Society for Computational Biology (ISCB) in 2015.[ 1] [ 22] Benjamin Franklin Award for open access in the life sciences.[ 2] [ 23]
^a b "ISCB Fellows" . International Society for Computational Biology. Archived fromthe original on 15 April 2015.^a b "Benjamin Franklin Award - Bioinformatics.org" .www.bioinformatics.org . Retrieved16 March 2018 .^a b c Desmond G. Higgins publications indexed byGoogle Scholar ^a b Notredame, C. D.; Higgins, D. G.; Heringa, J. (2000). "T-coffee: A novel method for fast and accurate multiple sequence alignment".Journal of Molecular Biology .302 (1):205– 17.doi :10.1006/jmbi.2000.4042 .PMID 10964570 .S2CID 10189971 . ^ "Des Higgins, PhD: Computational Biology Tree" .academictree.org . Archived fromthe original on 14 July 2017.^ Sharp, Paul M.; Cowe, Elizabeth;Higgins, Desmond G. ; Shields, Denis C.;Wolfe, Kenneth H. ; Wright, Frank (1988)."Codon usage patterns in Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens; a review of the considerable within-species diversity" .Nucleic Acids Research 16 (17):8207– 8211.doi :10.1093/nar/16.17.8207 .ISSN 0305-1048 .PMC 338553 PMID 3138659 . ^ Des Higgins atLibrary of Congress ^ Higgins, Desmond G.;Sharp, Paul M. (1988). "CLUSTAL: a package for performing multiple sequence alignment on a microcomputer".Gene .73 (1):237– 244.doi :10.1016/0378-1119(88)90330-7 .PMID 3243435 . ^ Higgins, Desmond G.;Sharp, Paul M. (1989). "Fast and sensitive multiple sequence alignments on a microcomputer".Bioinformatics .5 (2):151– 153.doi :10.1093/bioinformatics/5.2.151 .PMID 2720464 . ^a b Thompson, J. D.; Gibson, T. J.; Plewniak, F.; Jeanmougin, F.; Higgins, D. G. (1997)."The CLUSTAL_X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools" .Nucleic Acids Research .25 (24):4876– 4882.doi :10.1093/nar/25.24.4876 .PMC 147148 PMID 9396791 . ^a b Thompson, J. D.; Higgins, D. G.; Gibson, T. J. (1994)."CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice" .Nucleic Acids Research .22 (22):4673– 4680.doi :10.1093/nar/22.22.4673 .PMC 308517 PMID 7984417 . ^a b "Professor Desmond Gerard Higgins B.A.(Mod), PhD" . Dublin: University College Dubin. Archived fromthe original on 5 April 2015.^ "Des Higgins laboratory" . University College Dublin. Archived fromthe original on 14 December 2014.^ Desmond G. Higgins publications fromEurope PubMed Central ^ Des Higgins: Visualizing Multiple Sequence Alignments YouTube , Broad Institute^ Van Noorden, R.; Maher, B.;Nuzzo, R. (2014)."The top 100 papers: Nature explores the most-cited research of all time" .Nature 514 (7524):550– 3.doi :10.1038/514550a PMID 25355343 . ^ Gorey, Colm (2014)."Irish professor Des Higgins in top 10 most cited papers of all time" . Dublin: siliconrepublic.com. Archived fromthe original on 5 June 2015. ^ Desmond G. Higgins publications indexed by theScopus bibliographic database.(subscription required) ^a b Des HigginsORCID 0000-0002-3952-3285 ^ Sherlock, D.J.M. (2006).Trinity College Record Volume 2006 . Dublin: Trinity College Dublin Press.ISBN 1-871408-07-5 ^ Higgins, Des (1981).A numerical taxonomy of Pterygote insects (PhD thesis). Trinity College, Dublin.OCLC 842505334 .ProQuest 301410442 . ^ "Prof Des Higgins to Receive Kimura Motoo Award" .UCD School of Medicine . Retrieved31 May 2021 .^ "EMBL Alumni Awards Announced for 2023" .EMBL Alumni Awards . 29 March 2023. Retrieved31 March 2023 .
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International National Academics Other
