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David George Clayton (born 13 June 1944), is a Britishstatistician andepidemiologist. He is titular Professor ofBiostatistics in theUniversity of Cambridge andWellcome Trust and Juvenile Diabetes Research Foundation Principal Research Fellow in the Diabetes and Inflammation Laboratory, where he chairs the statistics group. Clayton is anISI highly cited researcher placing him in the top 250 most cited scientists in the mathematics world over the last 20 years.

Clayton has worked in theoretical and applied statistics, bothfrequentist andBayesian. WithNorman Breslow he has published important work ongeneralized linear mixed models. Clayton was a pioneer in the application ofMCMC methods to problems in biostatistics. More recently, he has worked ingenetic epidemiology.

Clayton readNatural Sciences atKing's College, Cambridge and following this worked as a researcher inergonomics andcybernetics. He then worked as a statistician at theLondon School of Hygiene and Tropical Medicine, theUniversity of Leicester and the MRC Biostatistics Unit in Cambridge before taking up his present position.

He was awarded theGuy Medal in Silver of theRoyal Statistical Society in 1990 and, with Norman Breslow, the Snedecor Prize of theCommittee of Presidents of Statistical Societies of North America (COPSS) in 1995. He was a lead statistician for theWellcome Trust Case Control Consortium, agenome-wide association study.

• "David Clayton: Brief biography". Cambridge Institute for Medical Research. Archived fromthe original on 19 November 2007. Retrieved3 March 2008.
• Clayton, David and Michael Hills (1993)Statistical Models in Epidemiology Oxford University Press.ISBN 0-19-852221-5
• "ISI Highly Cited David George Clayton". Retrieved19 August 2008.

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