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DPI-287

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Chemical compound

Pharmaceutical compound

DPI-287
Identifiers

IUPAC name 4-[(R)-[(2S,5R)-2,5-dimethyl-4-benzylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N,N-diethylbenzamide
CAS Number	519058-13-0^Y
PubChemCID	21025820
CompTox Dashboard(EPA)	DTXSID501018407
Chemical and physical data
Formula	C₃₁H₃₉N₃O₂
Molar mass	485.672 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCN(CC)C(=O)c2ccc(cc2)C(c(ccc4)cc4O)N(CC1C)C(C)CN1Cc3ccccc3
(verify)

DPI-287 is anopioid drug that is used in scientific research. It is a highly selectiveagonist for theδ-opioid receptor, which produces lessconvulsions than most drugs from this family.^[1] It hasantidepressant-like effects.^[2]

^Jutkiewicz EM (June 2006). "The antidepressant-like effects of delta-opioid receptor agonists".Molecular Interventions.6 (3):162–9.doi:10.1124/mi.6.3.7.PMID 16809477.
^Jutkiewicz EM, Chang KJ, Rice KC, Woods JH (2005). "Characterization of a novel nonpeptide delta-opioid agonist analog DPI287 with antidepressant-like activity".Experimental Biology Meeting Abstracts (Abstract # 874.4).