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DLST

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
DLST
Identifiers
AliasesDLST, DLTS, dihydrolipoamide S-succinyltransferase, PGL7, KGD2
External IDsOMIM:126063;MGI:1926170;HomoloGene:1456;GeneCards:DLST;OMA:DLST - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for DLST
Genomic location for DLST
Band14q24.3Start74,881,891bp[1]
End74,903,743bp[1]
Gene location (Mouse)
Chromosome 12 (mouse)
Chr.Chromosome 12 (mouse)[2]
Chromosome 12 (mouse)
Genomic location for DLST
Genomic location for DLST
Band12|12 D1Start85,157,607bp[2]
End85,181,619bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • apex of heart

  • right adrenal cortex

  • left ventricle

  • gastrocnemius muscle

  • left adrenal gland

  • left adrenal cortex

  • right auricle of heart

  • secondary oocyte

  • muscle of thigh

  • skin of leg
Top expressed in
  • right ventricle

  • muscle of thigh

  • digastric muscle

  • myocardium of ventricle

  • thoracic diaphragm

  • brown adipose tissue

  • right kidney

  • soleus muscle

  • cardiac muscles

  • sternocleidomastoid muscle
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

1743

78920

Ensembl

ENSG00000119689

ENSMUSG00000004789

UniProt

P36957

Q9D2G2

RefSeq (mRNA)

NM_001244883
NM_001933

NM_030225

RefSeq (protein)

NP_001231812
NP_001924

NP_084501

Location (UCSC)Chr 14: 74.88 – 74.9 MbChr 12: 85.16 – 85.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is anenzyme that in humans is encoded by theDLSTgene.[5][6]

Interactive pathway map

[edit]

Click on genes, proteins and metabolites below to link to respective articles.[§ 1]

  1. ^The interactive pathway map can be edited at WikiPathways:"TCACycle_WP78".

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000119689Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000004789Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Ali G, Wasco W, Cai X, Szabo P, Sheu KF, Cooper AJ, Gaston SM, Gusella JF, Tanzi RE, Blass JP (Jul 1994). "Isolation, characterization, and mapping of gene encoding dihydrolipoyl succinyltransferase (E2k) of human alpha-ketoglutarate dehydrogenase complex".Somat Cell Mol Genet.20 (2):99–105.doi:10.1007/BF02290679.PMID 8009371.S2CID 43092605.
  6. ^"Entrez Gene: DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)".

Further reading

[edit]
Photosynthesis
Dehydrogenase
Other


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