 | |
| Names | |
|---|---|
| IUPAC name 3,4-Dihydroxy-D-phenylalanine | |
| Systematic IUPAC name (2R)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
| ECHA InfoCard | 100.024.858 |
| UNII | |
| |
| |
| Properties | |
| C9H11NO4 | |
| Molar mass | 197.19 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
d-DOPA(D-3,4-dihydroxyphenylalanine;dextrodopa) is similar toL-DOPA (levodopa), but with oppositechirality.[1]Levo- anddextro- rotation refer to a molecule's ability to rotate planes ofpolarized light in one or the other direction. WhereasL-DOPA is moderately effective in thetreatment ofParkinson's disease (PD) anddopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain,D-DOPA isbiologically inactive.
Avoiding unwanted production ofD-DOPA is a goal for commercial synthesis ofL-DOPA-based drugs to treat Parkinson's disease.[1]
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