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Cubist Pharmaceuticals

Coordinates:42°25′25.2″N71°14′32.9″W / 42.423667°N 71.242472°W /42.423667; -71.242472
From Wikipedia, the free encyclopedia
Defunct American pharmaceutical company
Cubist Pharmaceuticals, Inc.
Company typeSubsidiary
Nasdaq: CBST
IndustryPharmaceuticals (Biopharmaceuticals & Biotherapeutics)
Founded1992; 33 years ago (1992)
Defunct2015 (2015)
HeadquartersLexington, Massachusetts
Key people
Robert J. Perez (president &CEO)
ProductsProduct Pipeline
RevenueIncrease $926.4 millionUSD (2012)
ParentMerck & Co.
Websitewww.cubist.com

Cubist Pharmaceuticals, Inc. was an Americanbiopharmaceutical company that targeted pathogens likeMRSA.

.[1] The company employed 638 people, mostly inLexington, Massachusetts.[2] On 8 December 2014,Merck & Co. acquired Cubist for $102 per share in cash ($8.4 billion).[3]

History

[edit]

Cubist was founded in May 1992 by John K. Clarke,Paul R. Schimmel, Ph.D. and Barry M. Bloom, Ph.D, all of whom were also directors.[4]Cubist appeared on Fortune 2010’s List of fastest growing companies, and was named to the 2010 Deloitte Technology Fast 500.[5]

In 2011, the company acquired Adolor, maker of a drug for treatment ofconstipation.[6]

The company expected sales of its drug Cubicin to grow to more than 1 billion dollars per year.

In July 2013, Cubist Pharmaceuticals agreed to purchaseTrius Therapeutics andOptimer Pharmaceuticals for around $1.6 billion.[7]

In 2014, succeedingMichael Bonney as President, Robert J. Perez, was announced to take leadership on January 1, 2015.[8]

In January 2015 Cubist Pharmaceuticals became a wholly owned subsidiary of Merck & Co.

Products

[edit]

The company developed Cubicin (daptomycin) for injection, the first antibiotic in a class of anti-infectives calledlipopeptides. In 2011, Cubist settled a patent litigation withTeva Pharmaceutical Industries regarding Cubicin.[9]In April 2011 it reached a deal with Optimer Pharmaceuticals in which its class of bacterium-fighting drugs will be co marketed with Optimer's Fidaxomicin/Dificid (for $15 million per year).[10]

In 2011, its product pipeline focused on gram-negative bacterial infections,[11]Clostridioides difficile infection,[12] andrespiratory syncytial virus.[13]

Tedizolid was approved by the USFood and Drug Administration on June 20, 2014.[14][15]

References

[edit]
  1. ^Mullin, Emily (26 Aug 2014)."Cubist exec: Challenges mount in antibiotics discovery".Fiercebiotechresearch.com. Retrieved23 Nov 2014.
  2. ^"Cubist Pharmaceuticals Inc. homesite".2009 Annual Report. Retrieved20 May 2011.
  3. ^Merck to take on superbugs with Cubist Pharma buy.Reuters, 9 December 2014
  4. ^"SEC Form S3 Cubist Pharmaceuticals, Inc". March 8, 2000.
  5. ^"100 FASTEST-GROWING COMPANIES".CNN. 2010. Retrieved28 May 2011.
  6. ^"Cubist Profit Down 53%",Drug Discovery & Development,Advantage Business Media, 19 Jan 2012, retrieved22 Jan 2012 – via Associated Press
  7. ^Vrinda Manocha and Zeba Siddiqui (30 July 2013)."Cubist to pay up to $1.6 billion for two antibiotics makers". Reuters.
  8. ^Weisman, Robert (20 Oct 2014)."New Cubist Pharmaceuticals chief executive will be Robert J. Perez".www.BostonGlobe.com. Retrieved23 Nov 2014.
  9. ^"Cubist Settles Teva Patent Litigation on Antibiotic Cubicin".Bloomberg. 2011-04-05. Retrieved28 May 2011.
  10. ^"Optimer to Market Dificid Drug With Cubist Pharmaceuticals".Bloomberg. 2011-04-06.
  11. ^Donnelly, Julie M. (13 December 2011)."Cubist advances antibiotic for Gram-negative bacteria".www.bizjournals.com. Retrieved2017-10-31.
  12. ^Brown, Rodney H. (6 April 2011)."Cubist – Optimer diarrhea drug could net $47M".www.bizjournals.com. Retrieved2017-10-31.
  13. ^"Alnylam Loses Cubist as RSV Partner, Stays Focused on ATTR Programs".GenomeWeb. Retrieved2017-10-31.
  14. ^Michael r. Page, Pharmd (17 September 2014)."Sivextro by Cubist Pharmaceuticals".www.pharmacytimes.com. September 2014.3 (5). Retrieved2017-10-31.
  15. ^"Cubist Announces FDA Acceptance of Tedizolid New Drug Application with Priority Review | FierceBiotech".www.fiercebiotech.com. 30 December 2013. Retrieved2017-10-31.
Corporate directors
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Schering-Plough
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42°25′25.2″N71°14′32.9″W / 42.423667°N 71.242472°W /42.423667; -71.242472

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