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Cormetasone

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Cormetasone
Clinical data
Other namesCormethasone; 6α,6β,9α-Trifluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
Drug classCorticosteroid;Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,16R,17R)-6,6,9-Trifluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-8,11,12,14,15,16-hexahydro-7H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC22H27F3O5
Molar mass428.448 g·mol−1
3D model (JSmol)
  • C[C@@H]1C[C@H]2[C@@H]3CC(C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)(F)F
  • InChI=1S/C22H27F3O5/c1-11-6-13-14-8-20(23,24)15-7-12(27)4-5-18(15,2)21(14,25)16(28)9-19(13,3)22(11,30)17(29)10-26/h4-5,7,11,13-14,16,26,28,30H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19+,21+,22+/m1/s1
  • Key:QVTPFMPYKMLGGK-QPZANWORSA-N

Cormetasone, orcormethasone, is asyntheticglucocorticoidcorticosteroid which was never marketed.[1]

References

[edit]
  1. ^Elks J (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 315–.ISBN 978-1-4757-2085-3.


GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others


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