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| Other names | Cycloprolol; SL-75177 |
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| Formula | C18H29NO4 |
| Molar mass | 323.433 g·mol−1 |
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Cicloprolol (INNTooltip International Nonproprietary Name; developmental code nameSL-75177), orcycloprolol (BANTooltip British Approved Name), is aβ-adrenergic receptor antagonist (beta blocker) described as anantihypertensive agent which was never marketed.[1][2][3][4][5] It has weakpartial agonist orintrinsic sympathomimetic activity (30%) at theβ-adrenergic receptors.[4][2] This is higher than that of many other beta blockers but is lower than that ofxamoterol (45%).[4] The drug isselective for theβ1-adrenergic receptor.[3] It has been studied in the treatment ofheart failure.[3]
Thechemical structure of cicloprolol is very similar to that ofbetaxolol.
Cicloprolol can be synthesized starting from 4-benzyloxyphenol.[6][7]
