Chromosome 14 is one of the 23 pairs ofchromosomes inhumans. People normally have two copies of this chromosome. Chromosome 14 spans about 107 millionbase pairs (the building material ofDNA) and represents between 3 and 3.5% of the total DNA incells.
Thecentromere of chromosome 14 is positioned approximately at position 17.2 Mbp.
The following are some of the gene count estimates of human chromosome 14. Because researchers use different approaches togenome annotation their predictions of thenumber of genes on each chromosome varies (for technical details, seegene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.[4]
G-banding ideogram of human chromosome 14 in resolution 850 bphs. Band length in this diagram is proportional to base-pair length. This type of ideogram is generally used in genome browsers (e.g.Ensembl,UCSC Genome Browser).
G-banding patterns of human chromosome 14 in three different resolutions (400,[12] 550[13] and 850[3]). Band length in this diagram is based on the ideograms from ISCN (2013).[14] This type of ideogram represents actual relative band length observed under a microscope at the different moments during themitotic process.[15]
G-bands of human chromosome 14 in resolution 850 bphs[16]
^For cytogenetic banding nomenclature, see articlelocus.
^abThese values (ISCN start/stop) are based on the length of bands/ideograms from the ISCN book, An International System for Human Cytogenetic Nomenclature (2013).Arbitrary unit.
^gpos: Region which is positively stained byG banding, generallyAT-rich and gene poor;gneg: Region which is negatively stained by G banding, generallyCG-rich and gene rich;acenCentromere.var: Variable region;stalk: Stalk.
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