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Clinical data | |
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AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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Pharmacokinetic data | |
Excretion | urine |
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ECHA InfoCard | 100.002.902![]() |
Chemical and physical data | |
Formula | C10H12ClNO4 |
Molar mass | 245.66 g·mol−1 |
3D model (JSmol) | |
Melting point | 86 to 92 °C (187 to 198 °F) |
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Chlorphenesin carbamate (Maolate,Musil) is a centrally actingmuscle relaxant used to treat muscle pain andspasms.[1][2] Chlorphenesin carbamate is no longer used for this purpose in most developed nations due to the availability of much safer spasmolytics such asbenzodiazepines.
Other central effects include sedation,anxiolysis, and dizziness.
A related chemical, chlorphenesin (C9H11ClO3)without thecarbamate group, is used as a preservative in products such as cosmetics. It hasantifungal and someantibacterial properties, and is classified as an antifungal for topical use by the WHO.[3]
The major adverse effect from this preservative on skin isallergic contact sensitivity.[4][5] Systemic intoxication fromtransdermal use has not been observed, although the FDA discourages its use as an ingredient in nipple cream for nursing mothers.[6]