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Chlorothen

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Chemical compound

Pharmaceutical compound

Chlorothen
Clinical data

Trade names	Thenclor
Routes of administration	Oral
ATC code	none
Identifiers
IUPAC name N-[(5-chloro-2-thienyl)methyl]-N',N'-dimethyl-N-(2-pyridyl)ethane-1,2-diamine
CAS Number	148-65-2
PubChemCID	8993
ChemSpider	8645
UNII	Y6068K376I
ChEMBL	ChEMBL2110628
CompTox Dashboard(EPA)	DTXSID5074848
Chemical and physical data
Formula	C₁₄H₁₈ClN₃S
Molar mass	295.83 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc1sc(cc1)CN(c2ncccc2)CCN(C)C
InChI InChI=InChI=1S/C14H18ClN3S/c1-17(2)9-10-18(14-5-3-4-8-16-14)11-12-6-7-13(15)19-12/h3-8H,9-11H2,1-2H3 Key:XAEXSWVTEJHRMH-UHFFFAOYSA-N

Chlorothen (trade nameThenclor) is anantihistamine andanticholinergic.^[1]

^Bovet D (April 1950). "Introduction to antihistamine agents and antergan derivative".Annals of the New York Academy of Sciences.50 (9):1089–1126.Bibcode:1950NYASA..50.1089B.doi:10.1111/j.1749-6632.1950.tb39905.x.PMID 15413927.S2CID 83626460.

mAChRsTooltip Muscarinic acetylcholine receptors

See also: Receptor/signaling modulators; Nicotinic acetylcholine receptor modulators; Acetylcholine metabolism/transport modulators

nAChRsTooltip Nicotinic acetylcholine receptors

Agonists
(and PAMsTooltip positive allosteric modulators)

Antagonists
(and NAMsTooltip negative allosteric modulators)

See also: Receptor/signaling modulators; Muscarinic acetylcholine receptor modulators; Acetylcholine metabolism/transport modulators

Agonists

Antagonists

Agonists	Amthamine Betazole Dimaprit Histamine HTMT Impromidine L-Histidine UR-AK49
Antagonists	Bisfentidine Burimamide Cimetidine Dalcotidine Donetidine Ebrotidine Etintidine Famotidine Isolamtidine Lafutidine Lamtidine Lavoltidine (loxtidine) Lupitidine Metiamide Mifentidine Niperotidine Nizatidine Osutidine Oxmetidine Pibutidine Quisultazine (quisultidine) Ramixotidine Ranitidine Roxatidine Sufotidine Tiotidine Tuvatidine Venritidine Xaltidine Zolantidine

Agonists	α-Methylhistamine BP 2.94 Cipralisant (GT-2331) GT-2203 (VUF-5296) Histamine Imetit Immepip Immethridine (BP-1-5375) L-Histidine Methimepip Proxyfan SCH-50971 VUF-5297
Antagonists	A-349821 A-423579 ABT-239 ABT-652 AZD5213 Bavisant Betahistine Burimamide Ciproxifan Clobenpropit Conessine Enerisant GSK-189254 Impentamine Iodophenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Thioperamide VUF-5681

Agonists	4-Methylhistamine α-Methylhistamine Histamine L-Histidine OUP-16 VUF-8430
Antagonists	JNJ-7777120 Mianserin Seliforant Thioperamide Toreforant VUF-6002

See also: Receptor/signaling modulators; Monoamine metabolism modulators; Monoamine reuptake inhibitors

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