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Chloracyzine

From Wikipedia, the free encyclopedia
(Redirected fromChloracizine)
Chemical compound

Pharmaceutical compound
Chloracyzine
Identifiers
  • 1-(2-Chloro-10H-phenothiazin-10-yl)-3-(diethylamino)-1-propanone
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC19H21ClN2OS
Molar mass360.90 g·mol−1
3D model (JSmol)
  • CCN(CC)CCC(=O)N1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
  • InChI=1S/C19H21ClN2OS/c1-3-21(4-2)12-11-19(23)22-15-7-5-6-8-17(15)24-18-10-9-14(20)13-16(18)22/h5-10,13H,3-4,11-12H2,1-2H3
  • Key:ZZKWNLZUYAGVOT-UHFFFAOYSA-N

Chloracyzine is anantidepressant and coronaryvasodilator of thephenothiazine class, invented inRussia and used as an anti-anginal agent.[1] It was found not to haveantipsychotic activity, but was instead the first Russian tricyclic drug with antidepressant action.[2]

See also

[edit]

References

[edit]
  1. ^Baum T, Wendt RL, Bergey JL (1977). "Chapter 5: Antiarrhythmic and Antianginal Agents". In Clarke FH (ed.).Annual Reports in Medicinal Chemistry. Vol. 12. Elsevier Science. p. 46.doi:10.1016/S0065-7743(08)61543-2.ISBN 978-0-08-058356-3.
  2. ^ДС Данилов (2019). "История трициклических антидепрессантов и ее значение для современной психофармакотерапии" [History of tricyclic antidepressants and its impact on current psychopharmacotherapy].Социальная и клиническая психиатрия (in Russian).


Classes
Antidepressants
(Tricyclic antidepressants(TCAs))
Antihistamines
Antipsychotics
Anticonvulsants
Anticholinergics
Others


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