| Charcot–Bouchard aneurysm | |
|---|---|
| Other names | Miliary aneurysms, Microaneurysms |
| Specialty | Cardiology  |
| Diagnostic method | CT or MRI brain scan |
Charcot–Bouchard aneurysms areaneurysms of the brain vasculature which occur in smallblood vessels (less than 300micrometre diameter). Charcot–Bouchard aneurysms are most often located in thelenticulostriate vessels of thebasal ganglia and are associated withchronichypertension.[1] Charcot–Bouchard aneurysms are a common cause ofcerebral hemorrhage. Charcot–Bouchard aneurysm rupture might be linked to senile plaque formation in the Alzheimer's disease.[2]
Retinal microaneurysms are seen in conditions likediabetic retinopathy,[3]: 498 HIV related retinal microangiopathy,[3]: 467 sickle cell retinopathy,[3]: 533 idiopathic macular telangiectasia[3]: 601 etc. In diabetic retinopathy, due to breakdown inblood–retinal barrier, microaneurysms may leak plasma constituents into the retina, or it may thrombose.[3]: 498
If a Charcot–Bouchard aneurysm ruptures, it will lead to an intracerebral hemorrhage, which can causehemorrhagic stroke, typically experienced as a sudden focal paralysis or loss of sensation.[1]
Charcot–Bouchard aneurysms areaneurysms in the small penetratingblood vessels of the brain. They are associated withhypertension. The common artery involved is thelenticulostriate branch of themiddle cerebral artery. Common locations of hypertensivehemorrhages include theputamen,caudate,thalamus,pons, andcerebellum.[citation needed]
As with any aneurysm, once formed they have a tendency to expand and eventually rupture, in keeping with theLaw of Laplace.[4][5]
Usually not detected by CT angiography.[5]Retinal microaneurysms can be diagnosed usingophthalmoscopy,fundus photography,FFA, andOCT.[6]
Charcot–Bouchard aneurysms are named for the French physiciansJean-Martin Charcot andCharles-Joseph Bouchard.[7][8] Bouchard discovered these aneurysms during his doctoral research under Charcot.[9]
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