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| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral |
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| Formula | C17H23NO4 |
| Molar mass | 305.374 g·mol−1 |
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Cetraxate (INN) is an oralgastrointestinalmedication which has a cytoprotective effect.[1][2][unreliable medical source?]
Cetraxate is aprodrug oftranexamic acid. The latter is ahemostatic agent because it inhibits the activation ofplasminogen toplasmin. The result is to prevent excess loss of blood ingastrointestinal ulcers.The synthesis begins with theesterification of 3-(p-hydroxyphenyl)propionic acid (2) bytrans-4-cyanocyclohexanecarbonyl chloride (1). The product (3) is reduced tocetraxate (4) bycatalytic hydrogenation withhydrogen andRaney nickel.[3][4]

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