Cephamycins are a group ofβ-lactam antibiotics. They are very similar tocephalosporins, and the cephamycins are sometimes classified as cephalosporins.
Like cephalosporins, cephamycins are based upon thecephem nucleus. Unlike most cephalosporins, cephamycins are a very efficient antibiotic against anaerobic microbes.[citation needed]
Cephamycins were originally produced byStreptomyces, but synthetic ones have been produced as well.[citation needed]
Cephamycins possess amethoxy group at the 7-alpha position.[1]
In addition, cephamycins have been shown to be stable against extended-spectrum beta-lactamase (ESBL) producing organisms, although their use in clinical practice is lacking for this indication.[citation needed]
Cephamycins include:
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