Former names | Western Reserve College (1826–1882) Western Reserve University (1882–1967) Case School of Applied Science (1880–1947) Case Institute of Technology (1947–1967) |
|---|---|
| Motto | Historical: Christo et Ecclesiae (1827–1885) Lux (1885–1932)[1] |
Motto in English | "For Christ and the Church" (1827–1885) "Light" (1885–1932) |
| Type | Privateresearch university |
| Established | 1826; 199 years ago (1826) |
| Accreditation | HLC |
Academic affiliations | |
| Endowment | $2.397 billion (2024)[2] |
| President | Eric Kaler |
| Provost | Joy K. Ward |
Academic staff | 1,182 (fall 2024)[3] |
Administrative staff | 3,375 (fall 2024)[3] |
| Students | 12,475 (fall 2024)[3] |
| Undergraduates | 6,528 (fall 2024)[3] |
| Postgraduates | 5,947 (fall 2024)[3] |
| Location | ,, United States 41°30′14″N81°36′29″W / 41.504°N 81.608°W /41.504; -81.608 |
| Campus | Large city[5], 267 acres (1.08 km2)[4] |
| Newspaper | The Case Western Reserve Observer |
| Colors | CWRU Blue, white, and gray[6] |
| Nickname | Spartans[7] |
Sporting affiliations | |
| Mascot | Spartie |
| Website | case.edu |
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Case Western Reserve University (CWRU) is aprivateresearch university inCleveland, Ohio, United States. It was federated in 1967 by a merger between Western Reserve University, founded in 1826 by thePresbyterian Church, and the Case Institute of Technology, founded in 1880.[9][10] Case Western Reserve University comprises eight schools that offer more than 100 undergraduate programs and about 160 graduate and professional options across fields in STEM, medicine, arts, and the humanities. In 2024, the university enrolled 12,475 students (6,528 undergraduate plus 5,947 graduate and professional) from all 50 states and 106 countries and employed more than 1,182 full-time faculty members. The university's athletic teams, Case Western Reserve Spartans, play inNCAA Division III as a founding member of theUniversity Athletic Association.
Case Western Reserve University is a member of theAssociation of American Universities and isclassified among "R1: Doctoral Universities – Very high research activity".[11] According to theNational Science Foundation, in 2023 the university hadresearch and development (R&D) expenditures of $553.7 million, ranking it 18th among private institutions and 59th in the nation.[12]
Case alumni, scientists, and scholars have played significant roles in many scientific breakthroughs and discoveries. Case professorAlbert A. Michelson became the first American to win a Nobel Prize in science, receiving theNobel Prize in Physics. In total, seventeen Nobel laureates are associated with Case Western Reserve University.
Western Reserve College, the college of theConnecticut Western Reserve, was founded in 1826 inHudson, Ohio, as theWestern Reserve College and Preparatory School by thePresbyterian Church.[9][10] Western Reserve College, or "Reserve" as it was popularly called, was the first college in northern Ohio.[13] The school was called "Yale of the West"; its campus, now that of theWestern Reserve Academy, imitated that of Yale. It had the same motto, "Lux et Veritas" (Light and Truth), the same entrance standards, and nearly the same curriculum. It was different from Yale in that it was amanual labor college, in which students were required to perform manual labor, seen as psychologically beneficial.[14]
Western Reserve College's founders sought to instill in students an "evangelical ethos" and trainChristian ministers for Ohio, where there was an acute shortage of them. The college was located in Hudson because the town made the largest financial offer to help in its construction.[15]: 422 That town, about 30 miles southeast of Cleveland, had been an antislavery center from the beginning: its founder,David Hudson, was against slavery, and founding trusteeOwen Brown was a notedabolitionist who secured the location for the college. The abolitionistJohn Brown, who would lead the1859 raid on Harpers Ferry, grew up in Hudson and was the son of co-founder Owen Brown. Hudson was a major stop on theUnderground Railroad.
With Presbyterian influences of its founding, the school's origins were strongly though briefly associated with the pre-Civil Warabolitionist movement;[16] the abolition of slavery was the dominant topic on campus in 1831. The trustees were unhappy with the situation. The college's chaplain and Bible professor,Beriah Green, gave four sermons on the topic[17] and then resigned, expecting that he would be fired. PresidentCharles Backus Storrs took a leave of absence for health, and soon died. One of the two remaining professors,Elizur Wright, soon left to head theAmerican Anti-Slavery Society.[18]
Western Reserve was the first college west of theAppalachian Mountains to enroll (1832) and graduate (1836) anAfrican-American student,John Sykes Fayette.[19]Frederick Douglass gave thecommencement speech in 1854.[20]
In 1838, theLoomis Observatory was built by astronomerElias Loomis, and today remains the second oldestobservatory in the United States, and the oldest still in its original location.[21]
In 1852, theMedical School became the second medical school in the United States to graduate a woman,Nancy Talbot Clark. Five more women graduated over the next four years, includingEmily Blackwell andMarie Zakrzewska, giving Western Reserve the distinction of graduating six of the first eight female physicians in the United States.[22]
By 1875, Cleveland had emerged as the dominant population and business center of the region, and the city wanted a prominent higher education institution. In 1882, with funding fromAmasa Stone, Western Reserve College moved to Cleveland and changed its name to Adelbert College of Western Reserve University. Adelbert was the name of Stone's son.[23]

In 1877,Leonard Case Jr. began laying the groundwork for the Case School of Applied Science by secretly donating valuable pieces of Cleveland real estate to a trust. He asked his confidential advisor, Henry Gilbert Abbey, to administer the trust and to keep it secret until after his death in 1880.
On March 29, 1880, articles of incorporation were filed for the founding of theCase School of Applied Science. Classes began on September 15, 1881.[24] The school received its charter by the state ofOhio in 1882.
For the first four years of the school's existence, it was located in the Case family's home on Rockwell Street indowntown Cleveland. Classes were held in the family house, while the chemistry and physics laboratories were on the second floor of the barn.Amasa Stone's gift to relocate Western Reserve College to Cleveland also included a provision for the purchase of land in theUniversity Circle area, adjacent to Western Reserve University, for the Case School of Applied Science. The school relocated toUniversity Circle in 1885.
In 1921Albert Einstein came to the Case campus during his first visit to the United States, out of respect for thephysics work performed there. Besides noting the research done in theMichelson–Morley experiment, Einstein also met with physics professorDayton Miller to discuss his own research.[25]
DuringWorld War II, Case School of Applied Science was one of 131 colleges and universities nationally that took part in theV-12 Navy College Training Program which offered students a path to a Navy commission.[26]
Over time, the Case School of Applied Science expanded to encompass broader subjects, adopting the name Case Institute of Technology in 1947 to reflect the institution's growth.[23]
Led by polymer expertEric Baer in 1963, the nation's first stand-alone Polymer Science and Engineering program was founded, to eventually become the Department of Macromolecular Science and Engineering.[27]

Although the trustees of Case Institute of Technology and Western Reserve University did not formally federate their institutions until 1967, the institutions already shared buildings and staff when necessary and worked together often. One such example was seen in 1887, when Case physicistAlbert Michelson and Reserve chemistEdward Morley collaborated on the famousMichelson–Morley experiment.
There had been some discussion of a merger of the two institutions as early as 1890, but those talks dissolved quickly. In the 1920s, the Survey Commission on Higher Education in Cleveland took a strong stand in favor of federation and the community was behind the idea as well, but in the end all that came of the study was a decision by the two institutions to cooperate in founding Cleveland College, a special unit for part-time and adult students indowntown Cleveland.
By the 1960s, Reserve PresidentJohn Schoff Millis and Case PresidentT. Keith Glennan shared the idea that federation would create a complete university, one better able to attain national distinction. Financed by theCarnegie Corporation,Cleveland Foundation,Greater Cleveland Associated Foundation, and several local donors, a study commission of national leaders in higher education and public policy was charged with exploring the idea of federation. The Heald Commission, so known for its chair, formerFord Foundation PresidentHenry T. Heald, predicted in its final report that a federation could create one of the largest private universities in the nation.
In 1967, Case Institute of Technology, a school with its emphasis on engineering and science, and Western Reserve University, a school with professional programs and liberal arts, came together to form Case Western Reserve University.[28]
In 1968, theDepartment of Biomedical Engineering launched as a newly unified collaboration between theSchool of Engineering andSchool of Medicine as the first in the nation and as one of the firstBiomedical Engineering programs in the world.[29] The following year in 1969, the first Biomedical Engineering MD/PhD program in the world began at Case Western Reserve.[30]
The firstcomputer engineering degree program in the United States was established in 1971 at Case Western Reserve.

On August 18, 2003, the university unveiled a new logo and branding campaign that emphasized the "Case" portion of its name.[31] The decision to put emphasis on the "Case" portion of the name was motivated by issues related to name recognition of the existing CWRU acronym, especially outside of northeast Ohio.[31] In 2006, interimuniversity president Gregory Eastwood convened a task group to study reactions to the campaign. The panel's report indicated that it had gone so poorly that, "There appear to be serious concerns now about the university's ability to recruit and maintain high-quality faculty, fund-raising and leadership." Also, the logo was derided among the university's community and alumni and throughout northeastern Ohio; critics said it looked like "...a fat man with a surfboard."[32][33]
On May 9, 2003, the2003 Case Western Reserve University shooting occurred when Biswanath Halder entered the Peter B. Lewis Building of theWeatherhead School of Management where he killed graduate student Norman Wallace and wounded two professors. Halder took people in the building hostage, and they ran and barricaded themselves and hid during the seven hours that the gunman roamed the building, shooting indiscriminately. He was finally apprehended by a SWAT team. Halder was convicted on multiple felony counts and sentenced to life in prison; he lost a 2008 appeal.[34][35]
In March 2007, the Branding Task Group presented its recommendations; a key recommendation was to return a graphic identity that gave equal weight to both the "Case" and "Western Reserve" names.[36] As part of this, the creation of a new logo and wordmark was also recommended, with an implementation group to work with various stakeholders to develop a replacement logo and wordmark.[36] At a June 2nd meeting, the university's board of trustees approved a shift back to giving equal weight to "Case" and "Western Reserve".[37] In an open letter to the university community, interim president Eastwood admitted that "the university had misplaced its own history and traditions" with the 2003 branding changes.[38] Implementation of the new logo began July 1, 2007.[39][40] The replacement logo, informally known as the "sunburst", would last until 2023.[41][42] The "Forward Thinking" campaign was launched in 2011 by PresidentBarbara Snyder and raised $1 billion in 30 months. The board of trustees unanimously agreed to expand the campaign to $1.5 billion, which reached its mark in 2017.[43] The campaign ultimately raised $1.82 billion.[44]
A2020 United States presidential debate, the first of two, was held at the Samson Pavilion of theHealth Education Campus (HEC), shared by theCleveland Clinic.[45]
In February 2020, president Barbara Snyder was appointed the president ofAssociation of American Universities (AAU). Later that year, formerTulane University presidentScott Cowen was appointed interim president. On October 29, 2020,Eric W. Kaler, formerUniversity of Minnesota president, was appointed as the new Case Western Reserve University president, effective July 1, 2021.[46]
On 2 June 2023, the 16 year old "sunburst" logo was replaced by a new logo which retained the sun element, but presented a more simple design, new fonts and brighter colors.[47] The new logo was met with mixed feelings from students, some praising the font choice and colors.[47] Others disliked the removal of the university's establishment year, 1826, present on the 2007-2023 logo, and the redesign of the sun image.[48] The editorial board of Case Western Reserve's student paper,The Observer, expressed overall dissatisfaction with the new logo, describing it as "bland" and "an embarrassment and stains the reputation of success that built our historic institution."[48]Concerns were also expressed about the frequency of logo changes, as this was the third logo in 23 years.[47] Such frequent changes could harm the university's image and brand consistency and lead to a repeat of the 2003 logo situation reoccurring.[47]
| No. | President | From | To |
|---|---|---|---|
| 1 | Robert W. Morse | 1967 | 1970 |
| 2 | Louis A. Toepfer | 1970 | 1980 |
| 3 | David V. Ragone | 1980 | 1987 |
| 4 | Agnar Pytte | 1987 | 1999 |
| 5 | David H. Auston | 1999 | 2001 |
| 6 | James W. Wagner (interim) | 2001 | 2002 |
| 7 | Edward M. Hundert | 2002 | 2006 |
| 8 | Gregory L. Eastwood (interim) | 2006 | 2007 |
| 9 | Barbara R. Snyder | 2007 | 2020 |
| 10 | Scott S. Cowen (interim) | 2020 | 2021 |
| 11 | Eric W. Kaler | 2021 | present |

Case Western Reserve University's main campus is approximately 5 miles (8 km) east ofDowntown Cleveland in the neighborhood known asUniversity Circle, an area containing many educational, medical, and cultural institutions.[49]
The Case Quadrangle, known also to students as the Engineering Quad, contains most engineering and science buildings, notably theJohn D. Rockefeller Physics Building.[50] The Case Quad also houses administration buildings, includingAdelbert Hall. TheMichelson–Morley experiment occurred here, commemorated by a marker and theMichelson-Morley Memorial Fountain. The southernmost edge consists of athletic areas—Adelbert Gymnasium, Van Horn Field and the Veale Convocation, Recreation and Athletic Center (commonly referred to as the Veale Center). The Veale Center houses theHorsburgh Gymnasium and the Veale Natatorium.

The Flora Stone Mather Quadrangle is located north of Euclid Avenue between East Blvd., East 115th Street, and Juniper Road. TheFlora Stone Mather College Historic District is more strictly defined by the area between East Blvd, Bellflower Road, and Ford Road north of Euclid Avenue. Named for the philanthropist wife of prominent industrialistSamuel Mather and sister-in-law of the famous statesmanJohn Hay, the Mather Quad is home toWeatherhead School of Management,School of Law,Mandel School of Applied Social Sciences, and many departments of theCollege of Arts and Sciences.
On and near campus, CircleLink is a free public shuttle service in University Circle and Little Italy.[51] For citypublic transit, rail and bus access are managed by theGreater Cleveland Regional Transit Authority (RTA). The twoRed Line rapid train stations areLittle Italy–University Circle andCedar–University. Notably, the Red Line connects campus toCleveland Hopkins Airport andDowntown Cleveland. Thebus rapid transit (BRT)HealthLine runs down the center of campus alongEuclid Ave. Numerous RTA bus routes run through campus.[52]

The university in its present form consists of eight schools that offer more than 100 undergraduate programs and about 160 graduate and professional options.[53]
CWRU also supports over 100 interdisciplinary academic and research centers in various fields.[54] Its graduate medical education includesresidency andfellowship programs atUniversity Hospitals Cleveland Medical Center (also known as University Hospitals Case Medical Center) andThe MetroHealth System.[55][56]
| Undergraduate admissions statistics | |
|---|---|
| Admit rate | 28.7% ( |
| Yield rate | 13.8% ( |
| Test scoresmiddle 50%[i] | |
| SAT Total | 1440–1530 (among 43% ofFTFs) |
| ACT Composite | 32–35 (among 23% ofFTFs) |
| High schoolGPA | |
| Average | 3.8 |
| |
The undergraduate student body hails from all 50 states and over 90 countries.[58]
The six most popular majors arebiomedical engineering,biology/biological sciences,nursing,mechanical engineering, andpsychology. Since 2016, the top fields for graduating CWRU undergraduate students have been engineering, nursing, research and science, accounting and financial services, and information technology.[59]
In 2023, the university received 39,039 applications. It extended offers of admission to 11,193 applicants, or 28.7%. 73% of admitted students were from outside Ohio and 13% from outside the United States. 1,544 accepted students chose to enroll, a yield rate of 13.8%.[57]
Of the 43% of incoming students in 2023 who submittedSAT scores, the totalinterquartile range was 1440–1530; of the 23% of incoming students in 2023 who submittedACT scores, the interquartile range of composite scores was 32–35. Of allmatriculating students, the average high school GPA was 3.8. 71% of admitted students graduated in the top 10% of their high school class.[57]
| Academic rankings | |
|---|---|
| National | |
| Forbes[60] | 238 |
| U.S. News & World Report[61] | 51(tie) |
| Washington Monthly[62] | 148 |
| WSJ/College Pulse[63] | 238 |
| Global | |
| ARWU[64] | 151–200 |
| QS[65] | 294(tie) |
| THE[66] | 159 |
| U.S. News & World Report[67] | 176(tie) |
InU.S. News & World Report's 2025rankings, Case Western Reserve was ranked as tied for 51st among national universities and 160th among global universities.[68][69] The 2020 edition ofThe Wall Street Journal/Times Higher Education (WSJ/THE) rankings ranked Case Western Reserve as 52nd among US colleges and universities.[70]
In 2018, Case Western Reserve was ranked 37th in the category American "national universities" and 146th in the category "global universities" byU.S. News & World Report. In 2019U.S. News ranked it tied for 42nd and 152nd, respectively. Case Western Reserve was also ranked 32nd among U.S. universities—and 29th among private institutions—in the inaugural 2016 edition ofThe Wall Street Journal/Times Higher Education (WSJ/THE) rankings, but ranked tied for 39th among U.S. universities in 2019.[70]
Case Western Reserve University'sbiochemistry program is jointly administered with theCWRU School of Medicine, and was ranked 14th nationally in the latest rankings byBlue Ridge Institute for Medical Research.[71]
Case Western Reserve is noted (among other fields) for research inelectrochemistry andelectrochemical engineering. TheMichelson–Morley interferometer experiment was conducted in 1887 in the basement of a campus dormitory byAlbert A. Michelson of Case School of Applied Science andEdward W. Morley of Western Reserve University. Michelson became the first American to win aNobel Prize in science.[72]
Also in 2018,The Hollywood Reporter ranked CWRU's Department of Theater Master of Fine Arts program with theCleveland Play House as 18th in the English-speaking world. In 2019, this ranking improved to 12th.[73]
In 2014,Washington Monthly ranked Case Western Reserve University as the 9th best National University,[74][75] but in the 2018 rankings, Case Western Reserve was ranked the 118th best National University.[76]
In 2013,Washington Monthly ranked Case Western Reserve as the nation's 4th best National University for contributing to the public good. The publication's ranking was based upon a combination of factors including social mobility, research, and service.[77] In 2009, the school had ranked 15th.[78] AlthoughWashington Monthly no longer ranks contributions to the public good as such, in its 2018 rankings of National Universities Case Western Reserve was ranked 180th in Social mobility and 118th in Service.[76]
In 2013, Case Western Reserve was among the Top 25 LGBT-Friendly Colleges and Universities, according to Campus Pride. The recognition follows Case Western Reserve's first five-star ranking on the Campus Pride Index, a detailed survey of universities' policies, services and institutional support for LGBT individuals.[79]
Case Western Reserve ranks 13th among private institutions (26th among all) in federal expenditures for science and engineering research and development, per theNational Science Foundation.[80]

Case Western Reserve University is a member of theAssociation of American Universities and isclassified among "R1: Doctoral Universities – Very high research activity".[11] Following is a partial list of major contributions made by faculty, staff, and students at Case Western Reserve since 1887:[citation needed]

Today, the university operates several facilities off campus for scientific research. One example of this is theWarner and Swasey Observatory atKitt Peak National Observatory inArizona.
CWRU has contributed to the electrochemical sciences since the 1930s beginning with Frank Hovorka's studies ofquinhydrone (quinone) and other electrodes. Subsequently, Ernest Yeager carried out pioneering studies on ultrasound electrodeposition andoxygen reduction reaction (ORR), which is directly relevant for H2-O2 fuel cells and batteries that use air electrodes such as zinc-air, iron-air, etc. The Yeager Center for Electrochemical Sciences (YCES), formerly the Case Center for Electrochemical Sciences, has provided annual workshops on electrochemical measurements since the late 1970s. The leadership in theElectrochemical Society have frequently included CWRU professors, and the university is home to six Fellows of the Electrochemical Society. Some notable achievements involve the work on ultrasound electrochemistry, oxygen reduction fundamentals, boron-doped diamond electrodes, in-situ electrochemical spectroscopy, polybenzimidazole (PBI) membranes for high-temperature fuel cells (HT-PEM), methanol fuel cells, iron-based flow batteries, metal deposition studies, dendrite modeling and electrochemical sensors. Noted laboratories at Case include the Electrochemical Engineering and Energy Laboratory (EEEL), the Electrochemical Materials Fabrication Laboratory (EMFL), the Case Electrochemical Capacitor Fabrication Facility and the ENERGY LAB.
Larry Sears and Sally Zlotnick Sears think[box] is a public-access design and innovation center at Case Western Reserve University that allows students and other users to accessprototyping equipment and other invention resources. The makerspace is located in the Richey Mixon building, a seven-story, 50,000 sq. ft. facility behind the campus athletic center. Over $35 million has been invested in space including in large part from a funding of $10 million from alumni Larry Sears and his wife Sally Zlotnick Sears.[94][95] Larry Sears is an adjunct faculty member in the Department of Electrical Engineering and Computer Science at CWRU and the founder of Hexagram, Inc. (now ACLARA Wireless Technologies).[96]Many projects andstartup companies have come out of themakerspace.[97]
| Race and ethnicity[98] | Total | ||
|---|---|---|---|
| White | 42% | ||
| Asian | 23% | ||
| Foreign national | 14% | ||
| Hispanic | 10% | ||
| Other[a] | 6% | ||
| Black | 4% | ||
| Economic diversity | |||
| Low-income[b] | 15% | ||
| Affluent[c] | 85% | ||
The primary area for restaurants and shopping is theUptown district along Euclid Ave adjacent to campus. Cleveland'sLittle Italy is within walking distance. A campus shuttle runs toCoventry Village, a shopping district in neighboringCleveland Heights. Popular with students,Downtown Cleveland,Ohio City,Legacy Village, andShaker Square are all a short driving distance or accessible byRTA.

WRUW-FM (91.1 FM) is the campus radio station of Case Western Reserve University. WRUW broadcasts at a power of 15,000 watts and covers most of Northeast Ohio.
Case Western Reserve is also home to 19 performing ensembles.[99][100][101]
For performances, all students, ensembles, and a cappella groups use Harkness Chapel. The bands and orchestra also perform atSeverance Hall (the on-campus home of theCleveland Orchestra) andCIM's Kulas Hall.
Case Western Reserve had the firstABET-accredited program incomputer engineering.[102]
In 1968, the university formed a private company, Chi Corporation, to provide computer time to both it and other customers. Initially this was on aUnivac 1108 (replacing the precedingUNIVAC 1107), 36 bit,ones' complement machine.[103] The company was sold in 1977 to Robert G. Benson inBeachwood, Ohio becoming Ecocenters Corporation.

Project Logos, under ARPA contract, was begun within the department on a DEC System-10 (later converted toTENEX (BBN) in conjunction with connection to theARPANET) to develop a computer-aided computer design system. This system consisted in a distributed, networked, graphics environment, a control and data flow designer and logic (both hardware and software) analyzer. AnImlac PDS-1 with lightpen interrupt was the main design workstation in 1973, communicating with the PDP-10 over a display communications protocol written by Don Huff as a Master Thesis and implemented on the Imlac by Ted Brenneman. Graphics and animation became another departmental focus with the acquisition of anEvans & SutherlandLDS-1 (Line Drawing System-1), which was hosted by the DEC System-10, and later with the acquisition of the stand-alone LDS-2.
Case Western Reserve was one of the earliest universities connected to theARPANET, predecessor to theInternet. ARPANET went online in 1969; Case Western Reserve was connected in January 1971.[104] Case Western Reserve graduate Ken Biba published theBiba Integrity Model in 1977 and served on the ARPA Working Group that developed theTransmission Control Protocol (TCP) used on the Internet.
It was the first university to have an all-fiber-optic network, in 1989.[105]
At the inaugural meeting in October 1996, Case Western Reserve was one of the 34 charter university members ofInternet2.[106]
The university was ranked No. 1 inYahoo Internet Life's 1999 Most Wired College list.[107] There was a perception that this award was obtained through partially false or inaccurate information submitted for the survey,[108] and the university did not appear at all on the 2000 Most Wired College list (which included 100 institutions). The numbers reported were much lower than those submitted by Ray Neff in 1999.[109][110] The university had previously placed No. 13 in the 1997 poll.[111]
In August 2003, Case Western Reserve joined theInternet Streaming Media Alliance, then one of only two university members.[112]
In September 2003, Case Western Reserve opened 1,230 public wireless access points on the Case Western Reserve campus and University Circle.[113]
Case Western Reserve was one of the founding members of OneCleveland, formed in October 2003.[114] OneCleveland is an "ultra broadband" (gigabit speed) fiber optic network. This network is for the use of organizations in education, research, government, healthcare, arts, culture, and the nonprofit sector in Greater Cleveland.
Case Western Reserve's Virtual Worlds gaming computer lab opened in 2005. The lab has a large network ofAlienware PCs equipped with game development software such as theTorque Game Engine andMaya 3D modeling software. Additionally, it contains a number of specialized advanced computing rooms including a medical simulation room, aMIDI instrument music room, a 3D projection "immersion room", avirtual reality research room, and console room, which features video game systems such asXbox 360,PlayStation 3, andWii.[115] This laboratory can be used by any student in the Electrical Engineering and computer science department, and is heavily used for the Game Development (EECS 290) course.
First-year students are grouped into one of fourresidential colleges that are overseen by first-year coordinators. The Mistletoe, Juniper, and Magnolia residential colleges were established when the "First Year Experience" system was introduced, and Cedar was created in the fall of 2005 to accommodate a large influx of new students. In the fall of 2007, Magnolia was integrated into Mistletoe, however, it was later re-separated in the fall of 2012. The areas of focus for each college are – Cedar: visual and performing arts; Mistletoe: service leadership; Juniper: multiculturalism and Magnolia: sustainability.[116]
Nearly one-half of the campus undergraduates are said to be in afraternity or sorority. There are dozens of Greek organizations on campus.
The Office of Emergency Management prepares for various levels of emergencies on campus, such as chemical spills, severe weather, infectious diseases, and security threats. RAVE, a multi-platform emergency alerting system, is operated by Emergency Management for issuing emergency alerts and instructions for events on campus. The Office of Emergency Management also performsrisk assessment to identify possible safety issues and aims to mitigate these issues. Additionally,CERT is managed through Emergency Management, enabling faculty and staff members to engage in emergency preparedness. The Office of Emergency Management works closely with other campus departments, such as Police and Security Services, University Health Services, and Environmental Health and Safety, as well as community resources including city, state, and federal emergency management agencies.[117]
Case operates a police force of sworn officers as well as a security officers.[118] CWRU Police also works closely with RTA transit police, University Circle Police,Cleveland Police, East Cleveland Police, Cleveland Heights Police, University Hospitals Police Department, and other surrounding emergency services. Police and Security, with conjunction with the Emergency Management Office, conduct tabletop drills and full-scale exercises involving surrounding emergency services.[119]
Case Western Reserve University Emergency Medical Services (CWRU EMS) is a student-run all volunteer ambulance service and aNational Collegiate Emergency Medical Services Foundation member. Covering University Circle, CWRU EMS is run solely by undergraduates volunteers, who provides freebasic life support level treatment and transport to local hospitals.[120] Crews receive medical direction from University Hospitals.[121]

Starting in 1910, the Hudson Relay is an annual relay race event remembering and honoring the university relocation fromHudson, Ohio to Cleveland. Conceived by then-student, Monroe Curtis,[122] the relay race was run from the old college in Hudson, Ohio to the new university in University Circle. Since the mid-1980s, the race has been run entirely in the University Circle area. The race is a distance of 26 miles (42 km). It is held weekend before spring semester finals. Competing running teams are divided by graduating class. If a class wins the relay all four years, tradition dictates a reward of a champagne and steak dinner with the president of the university be awarded. Only six classes have won all four years—1982, 1990, 1994, 2006, 2011, and 2017.[123][124] The winning classes of each year is carved on an original boulder located behindAdelbert Hall.
Since 1976, the Film Society[125] of Case Western Reserve University has held ascience fiction marathon. The film festival, the oldest of its type, boasts more than 34 hours of non-stop movies, cartoons, trailers, and shorts spanning many decades and subgenres, using both film and digital projection. The Film Society, which is student-run and open to the public, also shows movies on Friday and Saturday evenings throughout the school year.

Case Western Reserve competes in 19 varsity sports—10 men's sports and 9 women's sports. All 19 varsity teams wear a commemorative patch on their uniforms honoring Case alumnus,M. Frank Rudy, inventor of theNike air-sole.[126] The Spartans' primary athletic rival is theCarnegie Mellon Tartans.DiSanto Field is home to thefootball, men's soccer, women's soccer, and track and field teams.
Case Western Reserve is a founding and current member of theUniversity Athletic Association (UAA). The conference participates in theNational Collegiate Athletic Association's (NCAA)Division III. Case Institute of Technology and Western Reserve University were also founding members of thePresidents' Athletic Conference (PAC) in 1958. The university remained a member of the PAC after the merger of Case Institute of Technology and Western Reserve University and until 1983. In the fall of 1984, the university joined theNorth Coast Athletic Conference (NCAC) as a charter member. The 1998–99 school year marked the final season in which the Spartans were members of the NCAC. As the university had held joint conference membership affiliation with the UAA and the NCAC for over a decade. In 2014, the football team began competing as an associate member of the PAC, as only four out of the eight UAA member institutions sponsored football.[127]

TheCase Western Reserve football team reemerged in the mid-2000s under the direction of Head CoachGreg Debeljak. The 2007 team finished undefeated earning the school's first playoff appearance and first playoff victory, winning against theWidener Pride.
Notable alumni includeJohn Charles Cutler, former surgeon general who violated human rights and led to deaths in theTuskegee Syphilis Study,Terre Haute prison experiments, and thesyphilis experiments in Guatemala;Anthony Russo andJoe Russo,Hollywood movie directors,Paul Buchheit, creator and lead developer ofGmail;Craig Newmark, billionaire founder ofCraigslist;Peter Tippett, developer of the anti-virus software Vaccine, whichSymantec purchased and turned into the popularNorton AntiVirus; Francis E. Sweeney the main suspect from the Cleveland Torso Murders also was a Case Alumnus.
Founders ofFortune 500 companies includeHerbert Henry Dow, founder ofDow Chemical,Art Parker, founder ofParker Hannifin, andEdward Williams, co-founder ofSherwin-Williams.
Other notable alumni includeLarry Hurtado,New Testament scholar;Harvey Hilbert, a zen master, psychologist and expert on post-Vietnam stress syndrome;Peter Sterling, neuroscientist and co-founder of the concept ofallostasis;Ogiame Atuwatse III, Tsola Emiko the 21st Olu of Warri – a historic monarch of the Itsekiri people in Nigeria's Delta region, andDonald Knuth, a leading expert on computer algorithms and creator of theTeX typesetting system.

| Year | Recipient | Prize | Details |
| 1955 | Polykarp Kusch | Physics | BS in physics in 1931 |
| 1960 | Donald A. Glaser | Physics | BS in physics in 1946 |
| 1971 | Earl W. Sutherland Jr. | Medicine | Professor and chair of pharmacology |
| 1980 | Paul Berg | Chemistry | PhD in 1952 |
| 1988 | George H. Hitchings | Medicine | Professor and researcher |
| 1994 | Alfred G. Gilman | Medicine | MD and PhD in 1969 |
| 1994 | George A. Olah | Chemistry | Professor and chair of chemistry |
| 1995 | Frederick Reines | Physics | Professor and chair of physics |
| 1998 | Ferid Murad | Medicine | MD and PhD in 1965. Former trustee of Case |
| 2003 | Paul C. Lauterbur | Physiology or Medicine | BS in chemistry |
| 2003 | Peter Agre | Chemistry | Instructor, 1978 Internal Medicine alumnus |
| 2004 | Edward C. Prescott | Economics | MS in operations research in 1964 |
| 2017 | Richard Thaler | Economics | BA in economics in 1967 |
The local Presbyterian church opened Western Reserve College at Hudson, OH, in 1826 to satisfy the pressing need for clergy in the Western Reserve. The college later moved to Cleveland and eventually became CASE WESTERN RESERVE UNIV.
Western Reserve (later Case-Western Rserev) University, Muskingum, Wooster, and Cedarville joined Frankling as Presbyterian-affiliated schools
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