Movatterモバイル変換

Carbuterol

From Wikipedia, the free encyclopedia

Chemical compound

Pharmaceutical compound

Carbuterol
Clinical data

ATC code	R03CC10 (WHO)
Legal status
Legal status	AU: S4 (Prescription only)
Identifiers
IUPAC name (RS)-{5-[2-(tert-butylamino)-1-hydroxyethyl]-2-hydroxyphenyl}urea
CAS Number	34866-47-2^Y
PubChemCID	36976
ChemSpider	33928^Y
UNII	0N12JR32MR
ChEMBL	ChEMBL2110780^N
CompTox Dashboard(EPA)	DTXSID00865737
ECHA InfoCard	100.047.491
Chemical and physical data
Formula	C₁₃H₂₁N₃O₃
Molar mass	267.329 g·mol⁻¹
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES O=C(Nc1cc(ccc1O)C(O)CNC(C)(C)C)N
InChI InChI=1S/C13H21N3O3/c1-13(2,3)15-7-11(18)8-4-5-10(17)9(6-8)16-12(14)19/h4-6,11,15,17-18H,7H2,1-3H3,(H3,14,16,19)^Y Key:KEMXXQOFIRIICG-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Carbuterol (INN;carbuterol hydrochlorideUSAN) is a short-actingβ₂ adrenoreceptor agonist.^[1]^[2]

^Wardell JR, Colella DF, Shetzline A, Fowler PJ (April 1974)."Studies on carbuterol (SK & F 40383-A), a new selective bronchodilator agent".The Journal of Pharmacology and Experimental Therapeutics.189 (1):167–84.PMID 4823290.
^DE 2032642, Lunts LH, Collin DT, "1-phenyl-2-aminäthanol-Derivate und Verfahren zu ihrer Herstellung un ihre Verwendung", published 1970, assigned to Allen & Hansburys Ltd

Agonists

Antagonists

Agonists

Antagonists

Agonists

Antagonists

Short-acting β₂ agonists	Bitolterol Carbuterol Fenoterol Isoetarine Pirbuterol Procaterol Reproterol Rimiterol Salbutamol (albuterol)^#/Levosalbutamol (levalbuterol) Terbutaline Tulobuterol
Long-acting β₂ agonists	Bambuterol Clenbuterol Formoterol/Arformoterol Salmeterol
Ultra-long-acting β₂ agonists	Abediterol Carmoterol Indacaterol Olodaterol Vilanterol
Other	Clorprenaline Ephedrine (+theophylline,+theophylline/phenobarbital,theophylline/hydroxyzine) Epinephrine^# Etafedrine Hexoprenaline Isoprenaline (isoproterenol) Methylephedrine Orciprenaline (metaproterenol) Racephedrine Tretoquinol

Eicosanoid inhibition

Leukotriene antagonists	Montelukast Pranlukast Zafirlukast
Arachidonate 5-lipoxygenase inhibitors	Zileuton
Thromboxane receptor antagonists	Ramatroban Seratrodast
Non-xanthinePDE4 inhibitors	Ibudilast Roflumilast

Others/unknown

Combination products

Thisdrug article relating to therespiratory system is astub. You can help Wikipedia byexpanding it.

Hidden categories: