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| Clinical data | |
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| Other names | Acamylophenine |
| AHFS/Drugs.com | International Drug Names |
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| ECHA InfoCard | 100.000.184 |
| Chemical and physical data | |
| Formula | C19H32N2O2 |
| Molar mass | 320.477 g·mol−1 |
| 3D model (JSmol) | |
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Camylofin is anantimuscarinic drug.[1]
Camylofin is asmooth muscle relaxant with bothanticholinergic action and directsmooth muscle action. Anticholinergic action is produced by inhibiting the binding ofacetylcholine tomuscarinic receptors, but the action is less pronounced.[citation needed] Direct smooth muscle relaxation is achieved by inhibitingphosphodiesterase type IV, which leads to increasedcyclic AMP and eventually reducedcytosolic calcium. Thus camylofin has a comprehensive action to relieve smooth musclespasm. It is used to treat stomach ache in infants and children. Usually it is given in combination withparacetamol to treat stomach ache, as well aspyrexia.[2]
TheHell–Volhard–Zelinsky halogenation on phenylacetic acid [103-82-2] (1) gives 2-Bromo-2-phenylacetyl bromide,CID:15621041 (2). Treatment withisoamyl alcohol [123-51-3] gives 3-methylbutyl bromo(phenyl)acetate [92018-48-9] (3). Alkylation with N,N-Diethylethylenediamine [100-36-7] (4) completed the synthesis ofCamylofin (5).