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Camptotheca

From Wikipedia, the free encyclopedia
Genus of flowering plants in the family Nyssaceae

Camptotheca
Camptotheca acuminata
Scientific classificationEdit this classification
Kingdom:Plantae
Clade:Tracheophytes
Clade:Angiosperms
Clade:Eudicots
Clade:Asterids
Order:Cornales
Family:Nyssaceae
Genus:Camptotheca
Decne.
Species

Camptotheca acuminata
Camptotheca lowreyana

Camptotheca (happy tree,cancer tree, ortree of life) is a genus of medium-sizeddeciduoustrees growing to 20 metres (66 ft) tall, native to southernChina and Tibet. The genus is usually included in thetupelo familyNyssaceae, but sometimes included (with the tupelos) in thedogwood familyCornaceae.

The name "happy tree" is a direct translation of theChinese namexǐ shù (Simplified Chinese:喜树).

There are two species:

The bark and stems ofC. acuminata contain thealkaloidcamptothecin.[1] Several chemicalderivatives of camptothecin are under investigation for or used as drugs for cancer treatment, includingirinotecan,topotecan,rubitecan.[2]

C. acuminata also contains the chemical compoundstrifolin andhyperoside.[1]

References

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Wikimedia Commons has media related toCamptotheca.
  1. ^abLi, S.; Zhang, Z.; Cain, A.; Wang, B.; Long, M.; Taylor, J. (2005)."Antifungal Activity of Camptothecin, Trifolin, and Hyperoside Isolated fromCamptotheca acuminata".Journal of Agricultural and Food Chemistry.53 (1):32–37.doi:10.1021/jf0484780.PMID 15631505.
  2. ^G. Samuelsson (2004).Drugs of Natural Origin: a Textbook of Pharmacognosy (5th ed.). Stokkholm: Swedish pharmaceutical press.ISBN 978-91-974318-4-2.
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