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Calamine

From Wikipedia, the free encyclopedia
(Redirected fromCalamine lotion)
Cream or lotion for treating skin conditions
Not to be confused withChamomile.
This article is about the medication. For other uses, seeCalamine (disambiguation).
Pharmaceutical compound
Calamine
A puddle of a thin pink lotion, next to a pink plastic bottle
A puddle of calamine lotion next to a pink plastic bottle
Combination of
zinc oxideastringent
ferric oxideantipruritic
Clinical data
PronunciationKAL-ə-mine[1]
Other namesCalamine lotion
License data
Routes of
administration		Topical
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChemCID
ChemSpider
KEGG
ChEMBL
Chemical and physical data
3D model (JSmol)
  • [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2]
  • InChI=1S/2Fe.4O.Zn/q2*+3;4*-2;+2
  • Key:CPYIZQLXMGRKSW-UHFFFAOYSA-N
Look up calamine in Wiktionary, the free dictionary.

Calamine, also known ascalamine lotion, is a medication made from powderedcalamine mineral that is used to treat milditchiness.[2][3] Conditions treated includesunburn, insect bites,poison ivy,poison oak, and other mild skin conditions.[4][5] It may also help dry out secretions resulting from skin irritation.[1] It is applied on the skin as acream orlotion.[2]

Side effects may include skin irritation.[4] It is considered to be safe inpregnancy.[4] Calamine is a combination ofzinc oxide and 0.5%ferric oxide (Fe2O3).[6] The lotion is produced with additional ingredients such asphenol andcalcium hydroxide.[6][7]

The use of calamine lotion dates back as far as 1500 BC.[8] It is on theWorld Health Organization's List of Essential Medicines.[9] Calamine is availableover-the-counter as ageneric medication.[5]

Medical uses

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Calamine is used to treatitchiness.[2] This includessunburn, insect bite, or other mild skin conditions.[4][5]

Effectiveness

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TheFDA recommends applying some topical over-the-counter skin products, such as calamine, to absorb the weeping of the skin caused by poisonous plants such aspoison ivy,poison oak, andpoison sumac. For relieving the pain or itching caused by these plants, the FDA document recommends a cold water compress and topicalcorticosteroids.[10]

References

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  1. ^ab"Calamine (topical) medical facts from Drugs.com".www.drugs.com.Archived from the original on 2017-11-07.
  2. ^abcBritish National Formulary: BNF 69 (69 ed.). British Medical Association. 2015. p. 801.ISBN 9780857111562.
  3. ^World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.).WHO Model Formulary 2008. World Health Organization. p. 303.hdl:10665/44053.ISBN 9789241547659.
  4. ^abcd"Aqueous Calamine Cream BP - Summary of Product Characteristics (SPC) - (eMC)".www.medicines.org.uk. 18 November 2016.Archived from the original on 30 December 2016. Retrieved29 December 2016.
  5. ^abcHamilton R (2015).Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 191.ISBN 9781284057560.
  6. ^abBraun-Falco O, Plewig G, Wolff HH, Burgdorf W (2012)."Topical Therapy".Dermatology (2nd ed.). Springer Science & Business Media. p. 1724.ISBN 9783642979316.Archived from the original on 2016-12-29.
  7. ^Ma JK, Hadzija B (2012)."Rheology in Pharmacy".Basic Physical Pharmacy. Jones & Bartlett Publishers. p. 327.ISBN 9780763757342.Archived from the original on 2016-12-30.
  8. ^Darnton-Hill I, Ahmed F, Samman S (2016)."The impact of micronutrients on inflammation and health in low-and middle-income countries.". In Bendich A, Deckelbaum RJ (eds.).Preventive Nutrition: The Comprehensive Guide for Health Professionals (5th ed.). Springer. pp. 597-644 (608).ISBN 9783319224312.Archived from the original on 2016-12-30.
  9. ^World Health Organization (2019).World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization.hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  10. ^"Outsmarting Poison Ivy and Other Poisonous Plants".U.S. Food and Drug Administration: Consumer Updates. 9 June 2021 [Originally posted c. June 2009, since updated but advice unchanged].Archived from the original on 5 June 2009.

External links

[edit]
  • "Calamine".Drug Information Portal. U.S. National Library of Medicine.
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