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CagZ

From Wikipedia, the free encyclopedia
Protein produced by Helicobacter pylori bacteria


Protein family
CagZ
crystal structure of cag-z from helicobacter pylori
Identifiers
SymbolCagZ
PfamPF09053
InterProIPR015139
Available protein structures:
Pfam  structures /ECOD  
PDBRCSB PDB;PDBe;PDBj
PDBsumstructure summary

In molecular biology,CagZ is aprotein produced byHelicobacter pylori (Campylobacter pylori). It is a 23 kDa protein consisting of a single compact L-shaped domain, composed of sevenalpha-helices that runantiparallel to each other. 70% of the amino acids are inalpha-helix conformation and nobeta-sheet is present. CagZ is essential for the translocation of thepathogenic protein CagA into hostcells.[1]

References

[edit]
  1. ^Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G (July 2004). "Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system".J. Mol. Biol.340 (4):881–9.doi:10.1016/j.jmb.2004.05.016.PMID 15223328.
This article incorporates text from the public domainPfam andInterPro:IPR015139
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