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Cadralazine

From Wikipedia, the free encyclopedia

Chemical compound

Pharmaceutical compound

Cadralazine
Clinical data


AHFS/Drugs.com	International Drug Names
ATC code	C02DB04 (WHO)
Identifiers
IUPAC name Ethoxy-N'-{6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl}carbohydrazide
CAS Number	64241-34-5^Y
PubChemCID	2515
ChemSpider	2420^N
UNII	8T96I3U713
ChEMBL	ChEMBL2106561^N
CompTox Dashboard(EPA)	DTXSID4048725
Chemical and physical data
Formula	C₁₂H₂₁N₅O₃
Molar mass	283.332 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(OCC)NNc1nnc(N(CC(O)C)CC)cc1
InChI InChI=1S/C12H21N5O3/c1-4-17(8-9(3)18)11-7-6-10(13-15-11)14-16-12(19)20-5-2/h6-7,9,18H,4-5,8H2,1-3H3,(H,13,14)(H,16,19)^N Key:QLTVVOATEHFXLT-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Cadralazine is anantihypertensive of thehydrazinophthalazine chemical class.^[1]

References

^McTavish D, Young RA, Clissold SP (October 1990). "Cadralazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension".Drugs.40 (4):543–60.doi:10.2165/00003495-199040040-00005.PMID 2083513.

v t e Nonsympatholyticvasodilatory antihypertensives (C02)
Nitrovasodilator (arterioles and venules)	Nitroprusside #
Hydrazinophthalazines (arterioles)	Hydralazine # Dihydralazine Endralazine Cadralazine Pildralazine
Potassium channel openers (arterioles)	Minoxidil Diazoxide
Calcium channel blockers (arterioles)	seelist
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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