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CYP76 family

From Wikipedia, the free encyclopedia
Group of cytochrome P450 enzymes

Cytochrome P450, family 76, also known asCYP76, is acytochrome P450family in landplants,[1][2] related to thebiosynthesis of many plantmonoterpenes andditerpenes such as8-hydroxygeraniol,[3][2]tanshinone andalkannin.[4][5] The first gene identified in this family is theCYP76A1 andCYP76A2 from theeggplant.[1]

References

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  1. ^abToguri, T; Kobayashi, O; Umemoto, N (19 October 1993). "The cloning of eggplant seedling cDNAs encoding proteins from a novel cytochrome P-450 family (CYP76)".Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression.1216 (1):165–9.doi:10.1016/0167-4781(93)90058-l.PMID 8218411.
  2. ^abHöfer, R; Dong, L; André, F; Ginglinger, JF; Lugan, R; Gavira, C; Grec, S; Lang, G; Memelink, J; Van der Krol, S; Bouwmeester, H; Werck-Reichhart, D (November 2013). "Geraniol hydroxylase and hydroxygeraniol oxidase activities of the CYP76 family of cytochrome P450 enzymes and potential for engineering the early steps of the (seco)iridoid pathway".Metabolic Engineering.20:221–32.doi:10.1016/j.ymben.2013.08.001.PMID 23933465.
  3. ^Collu G, Unver N, Peltenburg-Looman AM, van der Heijden R, Verpoorte R, Memelink J (November 2001)."Geraniol 10-hydroxylase, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis".FEBS Letters.508 (2):215–20.doi:10.1016/s0014-5793(01)03045-9.PMID 11718718.S2CID 45615763.
  4. ^Höfer, R; Boachon, B; Renault, H; Gavira, C; Miesch, L; Iglesias, J; Ginglinger, JF; Allouche, L; Miesch, M; Grec, S; Larbat, R; Werck-Reichhart, D (November 2014)."Dual function of the cytochrome P450 CYP76 family from Arabidopsis thaliana in the metabolism of monoterpenols and phenylurea herbicides".Plant Physiology.166 (3):1149–61.doi:10.1104/pp.114.244814.PMC 4226383.PMID 25082892.
  5. ^Bathe, Ulschan; Frolov, Andrej; Porzel, Andrea; Tissier, Alain (11 December 2019). "CYP76 Oxidation Network of Abietane Diterpenes in Lamiaceae Reconstituted in Yeast".Journal of Agricultural and Food Chemistry.67 (49):13437–13450.Bibcode:2019JAFC...6713437B.doi:10.1021/ACS.JAFC.9B00714.PMID 30994346.
CYP1
CYP2
CYP3 (CYP3A)
CYP4
CYP5-20
CYP21-49
CYP51-69
CYP71-99
CYP101-281
CYP301-499
CYP501-699
CYP701-999
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