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CP 42,096

From Wikipedia, the free encyclopedia
Cannabinoid agonist drug
Pharmaceutical compound
CP 42,096
Identifiers
  • (6aR,9R,10aR)-6,6-dimethyl-3-(5-phenylpentan-2-yloxy)-6a,7,8,9,10,10a-hexahydrobenzo[c]chromene-1,9-diol
CAS Number
PubChemCID
ChemSpider
Chemical and physical data
FormulaC26H34O4
Molar mass410.554 g·mol−1
3D model (JSmol)
  • CC(CCCC1=CC=CC=C1)OC2=CC(=C3[C@@H]4C[C@@H](CC[C@H]4C(OC3=C2)(C)C)O)O
  • InChI=1S/C26H34O4/c1-17(8-7-11-18-9-5-4-6-10-18)29-20-15-23(28)25-21-14-19(27)12-13-22(21)26(2,3)30-24(25)16-20/h4-6,9-10,15-17,19,21-22,27-28H,7-8,11-14H2,1-3H3/t17?,19-,21-,22-/m1/s1
  • Key:YIUCAHIOICYGOA-WNBFYKTCSA-N

CP 42,096 is ananalgesic drug which acts as acannabinoidagonist. It was developed byPfizer in the 1980s as part of the research that led to the development oflevonantradol,[1][2][3] and is more potent thanTHC but less potent than newer compounds such asCP 55,244.[4][5]

See also

[edit]

References

[edit]
  1. ^Howlett AC, Johnson MR, Melvin LS, Milne GM (March 1988). "Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model".Molecular Pharmacology.33 (3):297–302.PMID 3352594.
  2. ^Prescott WR, Martin BR (1990). "The evaluation of synthetic cannabimimetic congeners for discriminative stimulus and cataleptogenic effects in rats".NIDA Research Monograph.105: 421.OCLC 7457082.PMID 1652087.
  3. ^Koe BK (1999). "Levonantradol". In Nahas GG, Sutin KM, Harvey D, Agurell S, Pace N, Cancro R (eds.).Marihuana and Medicine. Totowa, NJ: Humana Press. pp. 553–560.doi:10.1007/978-1-59259-710-9_53.ISBN 978-1-4757-5717-0.
  4. ^Koe BK, Milne GM, Weissman A, Johnson MR, Melvin LS (February 1985). "Enhancement of brain [3H]flunitrazepam binding and analgesic activity of synthetic cannabimimetics".European Journal of Pharmacology.109 (2):201–12.doi:10.1016/0014-2999(85)90421-2.PMID 2986995.
  5. ^"Hexahydrocannabinol (HHC) and related substances"(PDF).European Monitoring Centre for Drugs and Drug Addiction. 2023.
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