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CEACAM8

From Wikipedia, the free encyclopedia
Mammalian protein found in Homo sapiens
CEACAM8
Available structures
PDBHuman UniProt search:PDBeRCSB
List of PDB id codes

2DKS,4Y88,4YIQ,4WTZ

Identifiers
AliasesCEACAM8, CD66b, CD67, CGM6, NCA-95, carcinoembryonic antigen related cell adhesion molecule 8, CEA cell adhesion molecule 8
External IDsOMIM:615747;HomoloGene:68205;GeneCards:CEACAM8;OMA:CEACAM8 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for CEACAM8
Genomic location for CEACAM8
Band19q13.2Start42,580,243bp[1]
End42,595,055bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • trabecular bone

  • bone marrow

  • bone marrow cells

  • testicle

  • mononuclear cell

  • monocyte

  • blood

  • granulocyte

  • spleen

  • mucosa of transverse colon
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

1088

n/a

Ensembl

ENSG00000124469

n/a

UniProt

P31997

n/a

RefSeq (mRNA)

NM_001816

n/a

RefSeq (protein)

NP_001807

n/a

Location (UCSC)Chr 19: 42.58 – 42.6 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known asCD66b (Cluster ofDifferentiation66b), is a member of thecarcinoembryonic antigen (CEA)gene family. Its main function iscell adhesion,cell migration, andpathogen binding.[3]


Use

[edit]

CEACAM8 is expressed exclusively ongranulocytes and used as granulocyte marker.

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000124469Ensembl, May 2017
  2. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^"Entrez Gene: CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


PDB gallery
  • 2dks: Solution structure of the first IG-like domain of human carcinoembryonic antigen related cell adhesion molecule 8
    2dks: Solution structure of the first IG-like domain of human carcinoembryonic antigen related cell adhesion molecule 8
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