| chemokine (C-C motif) ligand 25 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CCL25 | ||||||
| Alt. symbols | SCYA25, TECK, Ckb15 | ||||||
| NCBI gene | 6370 | ||||||
| HGNC | 10624 | ||||||
| OMIM | 602565 | ||||||
| RefSeq | NM_005624 | ||||||
| UniProt | O15444 | ||||||
| Other data | |||||||
| Locus | Chr. 19p13.2 | ||||||
| |||||||
Chemokine (C-C motif) ligand 25 (CCL25) is a smallcytokine belonging to the CCchemokine family that is also known as TECK (Thymus-Expressed Chemokine). CCL25 is believed to play a role in the development ofT-cells.[1] It ischemotactic forthymocytes,macrophages, anddendritic cells. CCL25 elicits its effects by binding to thechemokine receptorCCR9.[2][3] Human CCL25 is produced as aprotein precursor containing 151amino acids. The gene for CCL25 (scya25) is located on human chromosome 19.[4]
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