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Bruce McEwen | |
|---|---|
 Bruce McEwen in anNCCIH interview entitled "Stress and Your Body" | |
| Born | Bruce Sherman McEwen (1938-01-17)January 17, 1938[1] |
| Died | January 2, 2020(2020-01-02) (aged 81) |
| Education | Oberlin College (BS) Rockefeller University (PhD) |
| Known for | Allostatic load |
| Awards | Dale Medal of theSociety for Endocrinology, Karl Spencer Lashley Award (2005), Pasarow Award in Neuropsychiatry (2005), Goldman-Rakic Prize for Cognitive Neuroscience (2005), Gold Medal Award from the Society for Biological Psychiatry (2009), IPSEN Foundations Prize in Neuroplasticity (2010), IPSEN Foundations Prize in Endocrine Regulations (2017) |
| Scientific career | |
| Fields | neuroscience,biological psychiatry,endocrinology |
| Institutions | Rockefeller University,University of Minnesota |
| Thesis | Energy Metabolism in Cell Nuclei (1964) |
| Doctoral advisor | Alfred Mirsky |
| Doctoral students | Heather Cameron Robert Sapolsky |
Bruce Sherman McEwen (January 17, 1938 – January 2, 2020) was an Americanneuroendocrinologist and head of the Harold and Margaret Milliken Hatch Laboratory ofNeuroendocrinology atRockefeller University. He was known for his work on the effects of environmental and psychological stress, having coined the termallostatic load.
McEwen received his bachelor's degree in chemistry from Oberlin College and his Ph.D. in cell biology from Rockefeller University in 1964. The McEwen laboratory was at the forefront of estrogen and glucocorticoid action in the brain for decades. McEwen's group demonstrated for the first time that estrogen can increase dendritic spine density in the CA1 subfield of the hippocampus. In addition, his lab also discovered stress-induced dendritic retraction in the CA3 hippocampal subfield. By pioneering the role of both gonadal and adrenal steroid action in the brain, the McEwen laboratory helped develop the modern concept of stress. His research has focused onglucocorticoids,stress andneuronal degeneration.[2]
McEwen's notable students includeRobert Sapolsky,Elizabeth Gould,Catherine Woolley,Michael Meaney, andHeather Cameron.
McEwen was a former president of theSociety for Neuroscience and was a member of theNational Academy of Sciences, theAmerican Academy of Arts and Sciences and theNational Academy of Medicine.
McEwen published his first paper in 1959, and eventually published more than 700 peer-reviewed articles in journals includingNature,JAMA: The Journal of the American Medical Association, The New England Journal of Medicine, Neurobiology of Aging andThe Journal of Neuroscience. His expertise and work have been featured onABC, NBC, CNN, PBS, NPR, BBC, and inThe New York Times,The Wall Street Journal, and many others. He was co-author of the bookThe End of Stress As We Know It, with science writer Elizabeth Norton Lasley, and another bookThe Hostage Brain, with science writer Harold M. Schmeck Jr. He has received numerous awards including a share of the IPSEN Foundation Prize in Neuroplasticity, the Gold Medal award from theSociety for Biological Psychiatry, the Pasarow Award in Neuropsychiatry, theBritish Endocrine Society's Dale Medal, the Goldman-Rakic Prize for Cognitive Neuroscience from theBrain & Behavior Research Foundation and the Karl Spencer Lashley Award from the American Philosophical Society.
McEwen was on the Scientific Advisory Board of Anti-AgingGames.com[3] where he collaborated withNolan Bushnell, the founder of Atari, and with a team of world-renowned behavioral neuroscientists[4] to create memory, focus and relaxation games for healthy adults over the age of 35.
