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Boyce Thompson Institute

From Wikipedia, the free encyclopedia
Independent plant-based research group at Cornell University

TheBoyce Thompson Institute (previously:Boyce Thompson Institute for Plant Research) is an independent research institute devoted to usingplant sciences to improveagriculture, protect theenvironment, and enhancehuman health. The Boyce Thompson Institute (BTI) is located on the campus ofCornell University inIthaca, New York, United States, and is fully integrated in the research infrastructure of the university. Faculty at BTI are members of several Cornell Departments, including Plant Biology, Chemistry & Chemical Biology, Molecular Biology & Genetics, as well as Plant Pathology and Plant-Microbe Biology. BTI is governed by a board of directors, which is in part appointed by Cornell.

BTI main entrance

History

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William Boyce Thompson became wealthy from thecopper mining industry and visitedRussia in 1917, where he saw the effects of hunger on its people. This trip persuaded Thompson of the importance of ensuring food supply for the world population, and in 1920, he decided to establish the Institute for Plant Research. He wanted the institute to further the understanding of plants, to use this understanding for improving world food supply, and to promote conservation of natural areas.[1][2]

The founding managing director wasWilliam Crocker, an associate professor of plant physiology at theUniversity of Chicago who along withHerbert Hice Whetzel had been academic advisers to Thompson when he planned the institute.[2]

Yonkers

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The Yonkers building in 2009

Thompson named the institute in honor of his parents, Anne Boyce Thompson and William Thompson, and endowed it with $10 million. Subsequently, the BTI has been funded by government support and revenues from the licensing of institute patents. Thompson played an active role in the early years of BTI and sought to encourage commercial development of the institute's research results. Therefore, rather than locating BTI on a university campus, Thompson built the laboratories in 1924 across the street from his country estateAlder Manor, inYonkers, New York.[3]

The Yonkers campus, used by BTI until the 1970s, was leased out for use as late as 1997, and then sold to the City of Yonkers Board of Education in 1999. In 2015 the city sold the property for $4.25 million to Simone Development Cos.[4] As of 2015[update] the plans for the campus were to re-develop it into a mixed-use center with medical offices, restaurants and retail stores.[5]

Cornell University

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BTI remained on its Yonkers campus until the 1970s, when Yonkers property taxes and urban pollution posed major problems. Managing Director George L. McNew favored an affiliation with a major research university, and soon a 'bidding war' broke out betweenOregon State University andCornell University to attract BTI. The New York State Legislature wanted to keep BTI in New York and appropriated $8.5 million for construction of facilities on the Cornell campus if BTI agreed to stay.[6] Oregon also appropriated funds as a relocation incentive. Ultimately, it was decided that affiliation with Cornell offered the most varied research opportunities.

In 1978 a new 116,854 sq ft (10,856.1 m2) building designed byUlrich Franzen was built next to theCornell Veterinary School, and the move was made.[7] Although affiliated with Cornell, the institute maintains its independence with a separate endowment, Board of Directors, business office, and employee benefits program. Close ties between BTI and Cornell foster collaborative relationships.[8]

In 2015, in an effort to revamp the brand, the institute changed its name from Boyce Thompson Institute of Plant Research to Boyce Thompson Institute (BTI).[9]

Programs

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Faculty investigators at BTI conduct research on plants and other organisms, train postdoctoral fellows, graduate students and undergraduates, and teach classes through adjunct appointments atCornell University. Current faculty members at BTI are: Gary Blissard, Carmen Catala, Zhangjun Fei, Jim Giovannoni,Maria Harrison,Georg Jander, Magda Julkowska, Fay-Wei Li, Greg Martin, Lukas Mueller, Andrew Nelson, Eric Richards, Frank Schroeder, Aleksandra Skirycz, David Stern, andJoyce Van Eck.[10]

The Scientist magazine survey of post doctoral fellows ranked BTI the 12th best place to work.[11] For example, BTI is part of the consortium that is sequencing thetomatogenome and creating a database of genomic sequences and information on the tomato and related plants.[12]

Each summer, BTI's 10-week Plant Genome Research Experience for Undergraduates program enables undergraduates selected nationally to conduct individual research. BTI also runs after-school science enrichment programs at local grade schools.[citation needed]

BTI's research facilities, including the BTIMass Spectrometry Facility and the Plant Cell Imaging Center, are available to researchers fromCornell University andSUNY Cortland.[13]

Technology transfer

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HighFive

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TheHighFive cell line was originally developed at BTI. The cell line and its virus-free sub-clones remain the sole property ofBTI. The High Five cells have been used to produce the VLP-based HPV vaccineCervarix.[14]

See also

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References

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  1. ^"History Overview". cornell.edu. Archived fromthe original on March 27, 2010. RetrievedFebruary 10, 2010.
  2. ^ab"History Overview". Archived fromthe original on January 18, 2010. RetrievedFebruary 17, 2010.
  3. ^Hudson Valley Ruins: Alder Manor by Rob Yasinsac; hudsonvalleyruins.org
  4. ^Seward, Ardina."Old Yonkers Building Gets New Life".www.hamlethub.com. RetrievedMarch 11, 2016.
  5. ^"New office complex for Boyce Thompson site".lohud.com. RetrievedMarch 11, 2016.
  6. ^Cliness, Francis (July 26, 1973)."Session Starts in Albany With Expanded Agenda (subsscription required)".New York Times. RetrievedFebruary 17, 2010.
  7. ^Boyce Thompson Institute - Facility InformationArchived 2012-03-02 at theWayback Machine, cornell.edu
  8. ^Cornell.eduArchived July 19, 2011, at theWayback Machine
  9. ^"BTI name change reflects scope of discoveries, mission".www.news.cornell.edu. RetrievedMarch 11, 2016.
  10. ^"Welcome to Boyce Thompson Institute - Inspired by how plants work for humanity".Boyce Thompson Institute. RetrievedDecember 24, 2022.
  11. ^"Postdocs Blossom at Plant Science Centers".The Scientist. March 1, 2006.
  12. ^"Tomato genome project gets $1.8M".Cornell News. January 2007.
  13. ^"Facilities & Services". cornell.edu. Archived fromthe original on January 18, 2010. RetrievedFebruary 10, 2010.
  14. ^Schiller, John T.; Castellsagué, Xavier; Villa, Luisa L.; Hildesheim, Allan (August 2008)."An update of prophylactic human papillomavirus L1 virus-like particle vaccine clinical trial results".Vaccine.26 (Suppl 10):K53 –K61.doi:10.1016/j.vaccine.2008.06.002.PMC 2631230.PMID 18847557.

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