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| Botryomycosis | |
|---|---|
| Other names | Bacterial pseudomycosis |
| Specialty | Infectious disease |
| Frequency | Uncommon[1] |
Botryomycosis is abacterial skin infection that typically presents with crusted,purulentlarge bumps.[1] Sulphur granules generally discharge via sinuses, which heal leavingthin-skinned scars.[1]
There are only a handful of documented cases of botryomycosis in humans, and itspathogenesis is not completely understood. However, it is usually described in individuals with impairedimmunity, or with an underlying disease such asdiabetes mellitus,cystic fibrosis orHIV infection.
It is most frequently caused byStaphylococcus aureus, and less frequently byPseudomonas aeruginosa,E. coli,Proteus, andStreptococcus,Bacteroides.[1] Risk factors includeweak immune system, HIV, alcoholism, andJob syndrome.[1]
Diagnosis is by culture of the discharge.[1]
The disease was originally discovered byOtto Bollinger (1843–1909) in 1870, and its name was coined by Sebastiano Rivolta (1832–1893) in 1884. The name refers to its grape-like granules (Gr.botryo = grapes) and the mistakenly impliedfungal etiology (Gr.mykes = fungus).[2] In 1919 the bacterial origin of the infection was discovered.