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Binding domain

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Region of a protein which can bind to biomolecules with chemical specificity

Inmolecular biology,binding domain is aprotein domain whichbinds to aspecific atom or molecule, such ascalcium orDNA. A protein domain is a part of aprotein sequence and atertiary structure that canchange or evolve, function, and live by itself independent of the rest of the protein chain.^[1] Upon binding, proteins may undergo aconformational change. Binding domains are essential for the function of many proteins. They are essential because they help splice, assemble, and translate proteins.^[2]

Examples of binding domains include theZinc finger, which binds to DNA, andEF hand, which binds to calcium.^{[citation needed]}

^Phillips, DC (1966). "The three-dimensional structure of an enzyme molecule".Scientific American.215 (5):78–90.doi:10.1038/scientificamerican1166-78.PMID 5978599.
^Yong, J., T. J. Golembe, D. J. Battle, L. Pellizzoni, and G. Dreyfuss. "SnRNAs Contain Specific SMN-binding Domains That Are Essential for SnRNP Assembly".Molecular and Cellular Biology. U.S. National Library of Medicine, April 2004. Retrieved April 2017.

v t e Proteins
Processes	Protein biosynthesis Post-translational modification Protein folding Protein targeting Proteome Protein methods
Structures	Protein structure Protein structural domains Proteasome
Types	List of proteins Membrane protein Globular protein Globulin Edestin Albumin Fibrous protein Chromoprotein Photoreceptor protein Biliprotein Phycobiliprotein Phytochrome Lipocalin

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