 | |
 | |
| Names | |
|---|---|
| Preferred IUPAC name 2,2-Dimethyl-2H-1,3-benzodioxol-4-yl methylcarbamate | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
|
| ECHA InfoCard | 100.041.091 |
| KEGG |
|
| UNII | |
| |
| |
| Properties | |
| C11H13NO4 | |
| Molar mass | 223.23 g/mol |
| Pharmacology | |
| QP53AE03 (WHO) | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Bendiocarb is an acutely toxiccarbamateinsecticide used inpublic health andagriculture and is effective against a wide range of nuisance and disease vector insects. Many bendiocarb products are or were sold under the tradenames "Ficam" and "Turcam."
All bendiocarb-containing products in theUnited States were recently[when?] cancelled, after its manufacturers voluntarily chose to pull their products off the market, rather than conduct additional safety studies required by the EPA.[1] In other countries, it is still used in homes, industrial plants, and food storage sites to controlbedbugs,mosquitoes,flies,wasps,ants,fleas,cockroaches,silverfish, andticks but can be used against a wide variety of insects as well as snails and slugs. It is one of 12 insecticides recommended by theWorld Health Organization for use inmalaria control.[2]
Bendiocarb is not considered to be carcinogenic, but it is acutely toxic. Like other carbamates, it reversibly inhibitsacetylcholinesterase, an enzyme required for normal transmission of nerve impulses. Bendiocarb binds to the active site of this enzyme leading to an accumulation ofacetylcholine, which is required for the transmission of nerve impulses, at nerve muscle sites.[1]
Bendiocarb was invented in 1971 and was first introduced into the market byFisons Ltd. It is currently marketed byBayer CropScience andKuo Ching under various trade names: Ficam, Dycarb, Garvox, Turcam, Niomil, Seedox, Tattoo
Bendiocarb is highly toxic to birds and fish. In addition, recently, a study in bone marrow cells of Calotes versicolor lizard demonstrated that chronic exposure to this contaminant increases the level of cytoxicity and genotoxicity (Anisha et al., 2019). In mammalian tissue, carbamates are generally excreted rapidly and do not accumulate.[1]
Anisha, N.S.; Tumul, S., (2019). Evaluation of Genotoxic and Cytotoxic effects of BendioCarb in Bone Marrow cells of one Calotes Versicolor. Proceedings of the Zoological Society of India 18(1): 19-23
