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Barry Trost

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(Redirected fromBarry M. Trost)
American chemist

Barry Martin Trost
Barry M. Trost in June 2012
BornJune 13, 1941 (1941-06-13) (age 83)
Alma materUniversity of Pennsylvania B.S. (1963)
Massachusetts Institute of Technology Ph.D. (1965)
Known forTsuji–Trost reaction,Trost ligand,Atom economy
AwardsACS Award in Pure Chemistry(1977)
Ernest Guenther Award(1990)
William H. Nichols Medal(2000)
Arthur C. Cope Award(2004)
The Ryoji Noyori Prize(2013)
Linus Pauling Award (2015)
Scientific career
FieldsOrganic Chemistry
InstitutionsUniversity of Wisconsin–Madison
Stanford University
ThesisThe Structure and Reactivity of Enolate Anions (1965)
Doctoral advisorHerbert O. House
Doctoral studentsBrian Coppola
Michael J. Krische
F. Dean Toste
Guangbin Dong

Barry M. Trost (born June 13, 1941, inPhiladelphia) is an American chemist who is the Job and Gertrud Tamaki Professor Emeritus in the School of Humanities and Sciences atStanford University.[1] TheTsuji–Trost reaction and theTrost ligand are named after him. He is prominent for advancing the concept ofatom economy.[2][3]

Early life and education

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Trost was born inPhiladelphia, Pennsylvania on June 13, 1941. He studied at theUniversity of Pennsylvania and obtained his B.A. in 1962.[4] He then attended theMassachusetts Institute of Technology for graduate school, where he worked withHerbert O. House onenolate anions, theMannich reaction, and theRobinson annulation.[5][6][7] Trost graduated with his Ph.D. in 1965.

Independent career

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Trost moved to theUniversity of Wisconsin–Madison to begin his independent career, and was promoted to professor of chemistry in 1969, and the Vilas Research Professor in 1982.[4] In 1987, he moved toStanford University as professor of chemistry, and was appointed the Job and Gertrud Tamaki Professor of Humanities and Sciences in 1990. He previously served as chair of the department of chemistry.[4]

As of 2021[update], Trost has anh-index of 161 according toGoogle Scholar[8] and of 140 (1040 documents) according toScopus.[9]

Research

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Trost's research focused on chemical synthesis.[10] In order to build complex target molecules from simple molecules, Trost developed new reactions and reagents, and utilizedcascade reactions and tandem reactions.[10] Target molecules have potential applications as novel catalysts, as well as antibiotic and anti-tumor therapeutics.[11]

References

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  1. ^"Barry Trost | Department of Chemistry".chemistry.stanford.edu. RetrievedMay 24, 2021.
  2. ^Trost, Barry M. (1991). "Atom Economy: A Search for Synthetic Efficiency".Science.254 (5037):1471–1477.Bibcode:1991Sci...254.1471T.doi:10.1126/science.1962206.PMID 1962206.
  3. ^Trost, Barry M. (1995). "Atom Economy - A Challenge for Organic Synthesis: Homogeneous Catalysis Leads the Way".Angewandte Chemie International Edition.34 (3):259–281.doi:10.1002/anie.199502591.
  4. ^abcTrost, Barry M.; Toste, F. Dean; Pinkerton, Anthony B. (June 19, 2001)."Non-Metathesis Ruthenium-Catalyzed C−C Bond Formation".Chemical Reviews.101 (7):2067–2096.doi:10.1021/cr000666b.ISSN 0009-2665.PMID 11710241.
  5. ^House, Herbert O.; Trost, Barry M. (June 1, 1964)."The Mannich Reaction with 2-Methylcyclopentanone and 2-Methylcyclo hexanone1a".The Journal of Organic Chemistry.29 (6):1339–1341.doi:10.1021/jo01029a016.ISSN 0022-3263.
  6. ^House, Herbert O.; Trost, Barry M. (May 1, 1965)."The Chemistry of Carbanions. IX. The Potassium and Lithium Enolates Derived from Cyclic Ketones1".The Journal of Organic Chemistry.30 (5):1341–1348.doi:10.1021/jo01016a001.ISSN 0022-3263.
  7. ^House, Herbert O.; Trost, Barry M.; Magin, Ralph W.; Carlson, Robert G.; Franck, Richard W.; Rasmusson, Gary H. (August 1, 1965)."By-products of the Robinson Annelation Reaction with Cyclohexanone, Cyclopentanone, and Cyclopentane-1,2-dione1".The Journal of Organic Chemistry.30 (8):2513–2519.doi:10.1021/jo01019a004.ISSN 0022-3263.
  8. ^Barry Trost publications indexed byGoogle ScholarEdit this at Wikidata
  9. ^"Scopus preview – Trost, Barry M. – Author details – Scopus".www.scopus.com. RetrievedOctober 17, 2021.
  10. ^ab"Trost Group Home".Stanford University. March 30, 2017. RetrievedOctober 17, 2021.
  11. ^"Barry Trost".Department of Chemistry. RetrievedOctober 17, 2021.

Sources

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External links

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