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BU-LAD

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
BU-LAD
Clinical data
Other namesBU-LAD; BULAD; 6-Butyl-6-nor-LSD; 6-Butyl-6-nor-Lysergic acid diethylamide
Routes of
administration
Oral[1]
Drug classSerotonergic psychedelic;Hallucinogen
Legal status
Legal status
Identifiers
  • (6aR,9R)-7-butyl-N,N-diethyl-4,6,6a,7,8,9- hexahydroindolo[4,3-fg]quinoline-9-carboxamide
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC23H31N3O
Molar mass365.521 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)[C@@H]2C=C1c3cccc4[nH]cc(C[C@H]1N(C2)CCCC)c34
  • InChI=1S/C23H31N3O/c1-4-7-11-26-15-17(23(27)25(5-2)6-3)12-19-18-9-8-10-20-22(18)16(14-24-20)13-21(19)26/h8-10,12,14,17,21,24H,4-7,11,13,15H2,1-3H3/t17-,21-/m1/s1 checkY
  • Key:VTVHSIXDKKKTMT-DYESRHJHSA-N checkY
 ☒NcheckY (what is this?)  (verify)

BU-LAD, also known as6-butyl-6-nor-LSD or6-butyl-6-nor-lysergic acid diethylamide, is apsychedelic drug andanalogue oflysergic acid diethylamide (LSD) first described byDavid E. Nichols and colleagues in the 1980s.[2][3]

Use and effects

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According toAlexander Shulgin in his bookTiHKAL (Tryptamines I Have Known and Loved), BU-LAD is apsychedelic drug similar to LSD, but is significantly lesspotent than LSD, with a dose of 500 μgorally producing only mild effects.[1]

Interactions

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See also:Psychedelic drug § Interactions, andTrip killer § Serotonergic psychedelic antidotes

Chemistry

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Analogues

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Analogues of BU-LAD includeLSD,ETH-LAD,PRO-LAD,AL-LAD,PARGY-LAD, andMAL-LAD, among others.

See also

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References

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  1. ^abShulgin, Alexander;Shulgin, Ann (September 1997).TiHKAL: The Continuation.Berkeley, California:Transform Press.ISBN 0-9630096-9-9.OCLC 38503252.
  2. ^Nichols DE, Oberlender R, McKenna DJ (1991)."Stereochemical Aspects of Hallucinogenesis". In Watson RR (ed.).Biochemistry and Physiology of Substance Abuse. Vol. 3. Boca Raton, Fla.: CRC Press. pp. 1–39.ISBN 978-0-8493-4463-3.OCLC 26748320.TABLE 1 Effects of N-(6)-Alkyl Subtituents on LSD-Like Behavior and Serotonin Receptor Affinity in Rats [...]
  3. ^Hoffman AJ, Nichols DE (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives".Journal of Medicinal Chemistry.28 (9):1252–5.doi:10.1021/jm00147a022.PMID 4032428.

External links

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Tryptamines
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Lysergamides
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Ergolines
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