Andrea Califano | |
|---|---|
 | |
| Born | 1961 |
| Nationality | American |
| Education | University of Florence |
| Awards | Member of the National Academy of Sciences (since 2018) Fellow of the AAAS (since 2015) Fellow of the ISCB (since 2017) Fellow of the AACR (since 2024) Fellow of the IEEE (since 1997) |
| Scientific career | |
| Fields | Systems biology,computational biology,cancer genetics |
| Institutions | Chan Zuckerberg Biohub Columbia University Irving Medical Center |
| Website | califano |
Andrea Califano is an Americanbiologist. He is a Clyde and Helen Wu professor of Chemical and Systems Biology atColumbia University Irving Medical Center. He also has roles in the Departments of Biochemistry & Molecular Biophysics, Biomedical Informatics, and Medicine. Califano serves as the president of theChan Zuckerberg Biohub New York.
Califano earned his Ph.D. in physics from the University of Florence, Italy, in 1986. He then joined theIBM T.J. Watson Research Center,[1] where he became the program director of the IBM Computational Biology Center in 1997. He joined Columbia University in 2003.[2]
Califano serves on various editorial and scientific advisory boards, including the Board of Scientific Advisors of theNational Cancer Institute,[3]St. Jude Children's Hospital,Koch Institute for Integrative Cancer Research,[4] andThermo Fisher Scientific Inc..[5] He is also the co-founder and Chief Scientific Advisor ofDarwinHealth.[6]
Califano was appointed president of the Chan Zuckerberg Biohub New York in 2023.[7]
Califano is renowned for his work in reverse engineering gene regulatory networks and analyzing them to identify key tumor checkpoint modules.[8] This research has led to several clinical trials, including an N-of-1 study that analyzes patients with 14 untreatable, lethal cancers individually to prioritize therapeutic strategies.[9]
