Hovenia dulcis has been used in traditionalJapanese,Chinese, andKorean medicines to treat fever, parasitic infection, as a laxative, and a treatment of liver diseases, and as ahangover treatment.[3] Methods have been developed to extract ampelopsin on a larger scale, and laboratory research has been conducted with the compound to see if it might be useful as a drug in any of the conditions for which the parent plant has been traditionally used.[3]
In a trial of 60 patients with "nonalcoholic fatty liver disease," dihydromyricetin improved glucose and lipid metabolism and yielded potentially beneficial anti-inflammatory effects.[5]
A study of rats demonstrated pharmacological properties of DHM which suggest it would be a therapeutic candidate to treatalcohol use disorders.[6]
Dihydromyricetin shows poorbioavailability which limits its potential medicinal applications.[7]
Additional research is required before claims of human efficacy and application, necessary dosage, and solutions to poor bioavailability, are met with scientific validation.
Ampelopsin is a versatile compound with a range of applications in health, wellness, andcosmetics, including:
Anti-Alcohol Intoxication: DHM is widely used in hangover remedies due to its ability to accelerate alcohol breakdown in the liver and mitigate alcohol-induced damage.[8][3]
Liver Protection: It helps in protecting the liver fromtoxins and promoting liver health.[9]
Antioxidant and Anti-Inflammatory: DHM has strongantioxidant and anti-inflammatory properties, contributing to its potential in preventing and treating chronic diseases.[10]
Cardiovascular Health: Research indicates that DHM may lowerblood pressure and reducecholesterol levels, benefiting heart health.[11]
Cosmetic Applications: DHM is used in skincare products for its ability to protect skin from UV-induced damage and aging.[12]
^Chen S, Zhao X, Wan J, Ran L, Qin Y, Wang X, Gao Y, Shu F, Zhang Y, Liu P, Zhang Q, Zhu J, Mi M (September 2015). "Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial".Pharmacol Res.99:74–81.doi:10.1016/j.phrs.2015.05.009.PMID26032587.
