Amit Singh (born 18 March 1976) is an Indianmicrobiologist and professor in the Department of Microbiology & Cell Biology at theIndian Institute of Science. His research focuses onpathogenesis, including drug resistance mechanisms in bothmycobacterium tuberculosis (TB) andhuman immunodeficiency viruses (HIV).

Amit Singh was born on 18 March 1976.^[1] He earned a Bachelor of Science from theUniversity of Delhi, and a master's inBiotechnology from theIndian Institute of Technology Roorkee.^[2] In 2004, he completed a PhD under the supervision of ProfessorAnil Kumar Tyagi at the University of DelhiSouth Campus. Subsequently, he conducted postdoctoral research in the lab of Dr. Adrie JC Steyn at theUniversity of Alabama in Birmingham (UAB).^[3]

Upon returning to India in 2010 Singh held a Wellcome Trust-DBT Intermediate Fellowship at theInternational Centre for Genetic Engineering and Biotechnology. In January 2014 he became an assistant professor ofmicrobiology andcell biology at theIndian Institute of Science (IISc).^[4] He leads a research group at the Centre for Infectious Disease Research,^[5] investigating the mechanisms ofchronic human infections with a focus onMycobacterium tuberculosis andhuman immunodeficiency virus (HIV).^[6][7][8]

Singh has held a Wellcome Trust-DBT Senior Fellowship since 2016.^[9][10] He received the 2017/18National Bioscience Award for Career Development from theDepartment of Biotechnology of theGovernment of India.^[11]

Singh is a co-inventor on a patent titled "Shortening Tuberculosis Therapy and Reducing Relapse by Co-administering Chloroquine in TB and HIV-TB Co-infected Conditions," filed in 2020 and published in 2021.

In 2021, Singh was awarded theShanti Swarup Bhatnagar Prize for Science and Technology for his contributions to understanding host-pathogen interactions inMycobacterium tuberculosis and HIV.^[12] In 2022, Singh was included in theAsian Scientist 100 list.

• Singh, A; Crossman, DK; Mai, D; Guidry, L; Voskuil, MI; Renfrow, MB; Steyn, AJ (2009)."Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response".PLOS Pathog.5 (8) e1000545.doi:10.1371/journal.ppat.1000545.PMC 2718811.PMID 19680450. (Cited by 204 articles according toGoogle Scholar.)
• Singh, A; Guidry, L; Narasimhulu, KV; Mai, D; Trombley, J; Redding, KE; Giles, GI; Lancaster, JR Jr; Steyn, AJ (2007)."Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival".Proc Natl Acad Sci U S A.104 (28):11562–7.Bibcode:2007PNAS..10411562S.doi:10.1073/pnas.0700490104.PMC 1906726.PMID 17609386. (Cited by 154 articles according to Google Scholar.)

• Ashima Bhaskar, Manbeena Chawla, Mansi Mehta, Pankti Parikh, Pallavi Chandra, Devayani Bhave, Dhiraj Kumar, Kate S Carroll, Amit Singh. Reengineering redox sensitive GFP to measure mycothiol redox potential of Mycobacterium tuberculosis during infection. 2014.PLOS Pathogens. 10:1 e1003902. (Cited by 88 articles according to Google Scholar.)
• Rufai SB, Kumar P, Singh A, Prajapati S, Balooni V, Singh S. Comparison of Xpert MTB/RIF with line probe assay for detection of rifampin-monoresistant Mycobacterium tuberculosis.Journal of clinical microbiology. 2014 June;52 (6): 1846–52. (Cited by 76 articles according to Google Scholar.)
• Chawla M, Parikh P, Saxena A, Munshi M, Mehta M, Mai D, Srivastava AK, Narasimhulu KV, Redding KE, Vashi N, Kumar D. Adrie JC Steyn and Amit Singh. Mycobacterium tuberculosis WhiB4 regulatesoxidative stress response to modulate survival and dissemination in vivo.Molecular microbiology. 2012 September;85 (6): 1148–65. (Cited by 56 articles according to Google Scholar.)

• Prasad, R. (29 September 2018)."IISc team finds new approaches to kill TB bacteria".The Hindu. Retrieved11 January 2019.
• "How do TB bacteria develop resistance to common antibiotics? A new study at IISc attempts to answer this".Research Matters. 6 July 2017. Retrieved11 January 2019.

• Official home page at IISc

• N-BIOS Prize recipients
• Indian immunologists
• Indian microbiologists
• Indian virologists
• Academic staff of the Indian Institute of Science
• Delhi University alumni
• IIT Roorkee alumni
• University of Alabama at Birmingham alumni
• Living people
• 1976 births

• Articles with short description
• Short description matches Wikidata
• Use dmy dates from September 2019
• Use Indian English from September 2019
• All Wikipedia articles written in Indian English
• Date of birth not in Wikidata
• Articles with hCards