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Amflutizole

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Chemical compound

Pharmaceutical compound

Amflutizole
Clinical data

ATC code	none
Identifiers
IUPAC name 4-Amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid
CAS Number	82114-19-0^Y
PubChemCID	54833
ChemSpider	49508^Y
UNII	83N680M457
KEGG	D02896^Y
ChEMBL	ChEMBL2106558
CompTox Dashboard(EPA)	DTXSID00868642
Chemical and physical data
Formula	C₁₁H₇F₃N₂O₂S
Molar mass	288.24 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES FC(F)(F)c1cccc(c1)c2nsc(c2N)C(=O)O
InChI InChI=1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18)^Y Key:KVMCEGAWQYTFKC-UHFFFAOYSA-N^Y
(verify)

Amflutizole is axanthine oxidase inhibitor^[1] used for the treatment ofgout.

^O'Regan MH, Smith-Barbour M, Perkins LM, Cao X, Phillis JW (October 1994). "The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex".Neuropharmacology.33 (10):1197–201.doi:10.1016/S0028-3908(05)80010-3.PMID 7862255.S2CID 37262919.

P2X
(ATPTooltip Adenosine triphosphate)

CNTsTooltip Concentrative nucleoside transporters	6-Hydroxy-7-methoxyflavone Adenosine dMeThPmR Estradiol KGO-2142 KGO-2173 MeThPmR Phloridzin Progesterone
ENTsTooltip Equilibrative nucleoside transporters	Barbiturates Benzodiazepines Cilostazol Dilazep Dipyridamole Estradiol Ethanol Hexobendine NBMPR Pentoxifylline Progesterone Propentofylline
PMATTooltip Plasma membrane monoamine transporter	Decynium-22

XOTooltip Xanthine oxidase	Allopurinol Amflutizole Benzbromarone Caffeic acid Cinnamaldehyde Cinnamomum osmophloeum Febuxostat Myo-inositol Kaempferol Myricetin Niraxostat Oxipurinol Phytic acid Pistacia integerrima Propolis Quercetin Tisopurine Topiroxostat
Others	Aminopterin Azathioprine Methotrexate Mycophenolic acid Pemetrexed Pralatrexate Many others

Others

See also:Receptor/signaling modulators

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