 | |
| Names | |
|---|---|
| Preferred IUPAC name 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one | |
| Other names 3,7,9-Trihydroxy-1-methyl-6H-benzo[c]chromen-6-one | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
|
| ECHA InfoCard | 100.164.145 |
| KEGG |
|
| UNII | |
| |
| |
| Properties | |
| C14H10O5 | |
| Molar mass | 258.229 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Alternariol (commonly abbreviated as AOH) is a toxic metabolite ofAlternaria fungi.[1] It is an important contaminant in cereals and fruits.[2]Alternariol exhibitsantifungal andphytotoxic activity. It is reported to inhibitcholinesterase enzymes.[3] It is also amycoestrogen.
A 2017in vitroassay study reported alternariol to be afullandrogen agonist.[4]
The acute toxicity of AOH and AME is low, but in vitro the substances show a strongmutagenic andteratogenic effect. The substances are associated with the development of esophagealcancer.[5]
