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Adrian Hayday

From Wikipedia, the free encyclopedia
British immunologist (born 1956)

Adrian Hayday
Hayday in 2016
BornApril 1956 (age 69)
Alma mater
Awards
Scientific career
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ThesisStructure and activity of integrated polyoma viral DNA in transformed rat cells (1979)
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Website

Adrian Clive Hayday (born April 1956)[3] is a British immunologist who is the Kay Glendinning professor and chair in the Department ofImmunobiology atKing's College London and group leader at theFrancis Crick Institute in the UK.[4][5]

Education

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Hayday was educated atQueens' College, Cambridge, where he was awarded a Bachelor of Arts degree innatural sciences (biochemistry) in 1978.[2][1] He went on to complete his PhD inmolecular virology ofPolyomaviridae atImperial College London in 1982.[6]

Career and research

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Hayday began studying immunology as apostdoctoral researcher in 1982 atMassachusetts Institute of Technology (MIT) supervised bySusumu Tonegawa,[2][7] where he identified the molecular basis ofoncogene activation inBurkitt's lymphoma. Thereafter, he first described the genes defininggamma-delta T cells, an evolutionarily conserved yet wholly unanticipated set oflymphocytes. AtYale University,King's College London School of Medicine and theFrancis Crick Institute, Hayday established that gamma-delta T cells are distinct from otherT cells, commonly monitoring body-surface integrity rather than specific infections. Their rapid responses to tissue dysregulation offer protection fromcarcinogenesis, underpinning Hayday's and others' ongoing initiatives to employ the cells forimmunotherapy.[8]

Awards and honours

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Hayday has received numerous awards, including the William Clyde DeVane Medal, Yale's highest honour for scholarship and teaching. He was elected to head theBritish Society for Immunology (2005–09), and has formally counselledKing's Health Partners, thePasteur Institute,Kyoto University, theMax Planck Institute, the Allen Institute,MedImmune, theNational Institutes of Health, theWellcome Trust, andCancer Research UK whose science committee he chairs.[1] He was elected aFellow of the Royal Society (FRS) in 2016.[1]He is an honorary member of theBritish Society for Immunology.[9]

References

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  1. ^abcdAnon (2016)."Professor Adrian Hayday FRS". London:Royal Society. Archived fromthe original on 29 April 2016. One or more of the preceding sentences incorporates text from the royalsociety.org website where:

    "All text published under the heading 'Biography' on Fellow profile pages is available underCreative Commons Attribution 4.0 International License." --"Royal Society Terms, conditions and policies". Archived from the original on 25 September 2015. Retrieved9 March 2016.{{cite web}}: CS1 maint: bot: original URL status unknown (link)

  2. ^abcdAdrian Hayday'sORCID 0000-0002-9495-5793
  3. ^Anon (2016)."Adrian Clive HAYDAY". London: companieshouse.gov.uk. Archived fromthe original on 28 July 2016.
  4. ^Anon (2016)."Adrian Hayday: Immunosurveillance Laboratory".The Francis Crick Institute. London: crick.ac.uk. Archived fromthe original on 5 April 2015.
  5. ^Gibbons, Deena; Fleming, Paul; Virasami, Alex; Michel, Marie-Laure; Sebire, Neil J; Costeloe, Kate; Carr, Robert; Klein, Nigel; Hayday, Adrian (2014). "Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants".Nature Medicine.20 (10):1206–1210.doi:10.1038/nm.3670.PMID 25242415.S2CID 5849557.
  6. ^Hayday, Adrian Clive (1982).Structure and activity of integrated polyoma viral DNA in transformed rat cells (PhD thesis). Imperial College London.OCLC 930652868.
  7. ^Hayday, A (1985). "Structure, organization, and somatic rearrangement of T cell gamma genes".Cell.40 (2):259–269.doi:10.1016/0092-8674(85)90140-0.PMID 3917858.S2CID 34582929.
  8. ^Kiyokawa, Hiroaki; Kineman, Rhonda D; Manova-Todorova, Katia O; Soares, Vera C; Hoffman, Eric S; Ono, Masao; Khanam, Dilruba; Hayday, Adrian C; Frohman, Lawrence A; Koff, Andrew (1996)."Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27Kip1".Cell.85 (5):721–732.doi:10.1016/S0092-8674(00)81238-6.PMID 8646780.
  9. ^"Honorary members | British Society for Immunology".
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