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Adaprolol

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Chemical compound

Pharmaceutical compound

Adaprolol
Clinical data

ATC code	none
Identifiers
IUPAC name (±)-2-(1-adamantyl)ethyl 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetate
CAS Number	101479-70-3^N
PubChemCID	60732
ChemSpider	4940501^Y
UNII	XP9911I1WL
ChEMBL	ChEMBL435170^N
CompTox Dashboard(EPA)	DTXSID90869360
Chemical and physical data
Formula	C₂₆H₃₉NO₄
Molar mass	429.601 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(CC1=CC=C(OCC(O)CNC(C)C)C=C1)OCCC23C[C@@H]4C[C@H](C2)C[C@H](C3)C4
InChI InChI=1S/C26H39NO4/c1-18(2)27-16-23(28)17-31-24-5-3-19(4-6-24)12-25(29)30-8-7-26-13-20-9-21(14-26)11-22(10-20)15-26/h3-6,18,20-23,27-28H,7-17H2,1-2H3^N Key:IPGLIOFIFLXLKR-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Adaprolol is abeta blocker.^[1]^[2]

^"The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs". Archived fromthe original on March 7, 2012.
^Boder N, Elkoussi A, Zuobi K, Kovacs P (1996). "Synthesis and pharmacological activity of adaprolol enantiomers: a new soft drug for treating glaucoma".Journal of Ocular Pharmacology and Therapeutics.12 (2):115–22.doi:10.1089/jop.1996.12.115.PMID 8773927.

Central

α₂-Adrenergic receptor agonists	Clonidine Guanabenz Guanfacine Guanoxabenz Methyldopa^# Tiamenidine^‡
Adrenergic release inhibitors	Bethanidine Bretylium Debrisoquine Guanadrel Guanazodine Guancydine Guanethidine Guanoclor Guanoxan
Imidazoline receptor agonists	Moxonidine Rilmenidine Tolonidine
Ganglion-blocking/nicotinic antagonists	Hexamethonium^‡ Mecamylamine Pentolinium Trimethaphan

Peripheral

Indirect

Monoamine oxidase inhibitors	Pargyline^‡
VMAT inhibitors	Bietaserpine Deserpidine Methoserpidine Reserpine Syrosingopine
Tyrosine hydroxylase inhibitors	Metirosine

Direct

α₁-Adrenergic receptor blockers	Doxazosin Ketanserin Indoramin Prazosin Trimazosin Urapidil
Non-selective α-adrenergic receptor blockers	Phentolamine

Serotonin receptor antagonists	Ketanserin Lidanserin
Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension)	dual (Aprocitentan,Bosentan,Macitentan (+tadalafil),Riociguat) selective (Ambrisentan (+tadalafil),Sitaxentan,Sotatercept)