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Aclidinium bromide/formoterol

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Drug combination used to manage Chronic Obstructive Pulmonary Disease (COPD)

Pharmaceutical compound

Aclidinium bromide/formoterol
Combination of
Aclidinium bromide	Long-actingmuscarinic antagonist
Formoterol	Long-acting β₂ agonist
Clinical data
Trade names	Brimica Genuair, Duaklir Genuair, Duaklir Pressair
AHFS/Drugs.com	Professional Drug Facts
License data	US DailyMed: Duaklir
Pregnancy category	AU: B3
Routes of administration	Inhalation
ATC code	R03AL05 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only)^[1] US: ℞-only^[2] EU: Rx-only [3]^[4] In general: ℞ (Prescription only)
Identifiers
CAS Number	2446159-07-3
KEGG	D11857

Aclidinium bromide/formoterol, sold under the brand namesDuaklir andBrimica, is afixed-dose combination medication forinhalation, used in the management ofchronic obstructive pulmonary disease (COPD).^[5] It consists ofaclidinium bromide, a long-actingmuscarinic antagonist, andformoterol, along-acting β₂ agonist.^[3]^[4]

^"Duaklir Genuair 340 micrograms /12 micrograms inhalation powder - Summary of Product Characteristics (SmPC)".(emc). 9 September 2019. Archived fromthe original on 26 July 2020. Retrieved26 July 2020.
^"Duaklir Pressair- aclidinium bromide and formoterol fumarte powder, metered".DailyMed. 3 July 2020. Retrieved28 November 2020.
^^a ^b"Duaklir Genuair EPAR".European Medicines Agency (EMA). 18 May 2018. Retrieved26 July 2020.
^^a ^b"Brimica Genuair EPAR".European Medicines Agency (EMA). 18 May 2018. Retrieved26 July 2020.
^D'Urzo AD, Singh D, Donohue JF, Chapman KR, Wise RA (September 2021). "Aclidinium bromide/formoterol fumarate as a treatment for COPD: an update".Expert Review of Respiratory Medicine.15 (9):1093–1106.doi:10.1080/17476348.2021.1920403.PMID 34137664.S2CID 235460050.

"Aclidinium bromide".Drug Information Portal. U.S. National Library of Medicine. Archived fromthe original on December 12, 2020.
"Formoterol fumarate".Drug Information Portal. U.S. National Library of Medicine. Archived fromthe original on July 10, 2017.

Short-acting β₂ agonists	Bitolterol Carbuterol Fenoterol Isoetarine Pirbuterol Procaterol Reproterol Rimiterol Salbutamol (albuterol)^#/Levosalbutamol (levalbuterol) Terbutaline Tulobuterol
Long-acting β₂ agonists	Bambuterol Clenbuterol Formoterol/Arformoterol Salmeterol
Ultra-long-acting β₂ agonists	Abediterol Carmoterol Indacaterol Olodaterol Vilanterol
Other	Clorprenaline Ephedrine (+theophylline,+theophylline/phenobarbital,theophylline/hydroxyzine) Epinephrine^# Etafedrine Hexoprenaline Isoprenaline (isoproterenol) Methylephedrine Orciprenaline (metaproterenol) Racephedrine Tretoquinol

Eicosanoid inhibition

Leukotriene antagonists	Montelukast Pranlukast Zafirlukast
Arachidonate 5-lipoxygenase inhibitors	Zileuton
Thromboxane receptor antagonists	Ramatroban Seratrodast
Non-xanthinePDE4 inhibitors	Ibudilast Roflumilast