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Acetergamine

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(March 2024)
Acetergamine
Names
Systematic IUPAC name
N-{[(8β)-6-Methylergolin-8-yl]methyl}acetamide
Other names
8β-acetylaminomethyl-6-methylergoline
(+)-N-Acetyl-9,10-dihydrolysergamine
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard100.019.281Edit this at Wikidata
UNII
  • InChI=1S/C18H23N3O/c1-11(22)19-8-12-6-15-14-4-3-5-16-18(14)13(9-20-16)7-17(15)21(2)10-12/h3-5,9,12,15,17,20H,6-8,10H2,1-2H3,(H,19,22)/t12-,15+,17+/m0/s1
    Key: SGZVEWGAZGOWGP-XGWLTEMNSA-N
  • O=C(NC[C@@H]2C[C@@H]3c4cccc1c4c(c[nH]1)C[C@H]3N(C2)C)C
Properties
C18H23N3O
Molar mass297.402 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

Acetergamine is anorganic chemical compound; specifically it is a derivative ofergoline, making it a member of theergotamine family of compounds. Acetergamine currently has no mainstream uses, however its potential as analpha-1 blocker andvasodilator has led to it being covered in several patents concerning therapies for erectile dysfunction. It has also been investigated as a treatment forcerebellar ataxia.[1]

References

[edit]
  1. ^Ogawa, M (2004). "Pharmacological treatments of cerebellar ataxia".Cerebellum.3 (2). London):107–11.doi:10.1080/147342204100032331.PMID 15233578.S2CID 21026074.


α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists
Ergolines
(incl.lysergines)
Clavines
(6,8-dimethylergolines)
Lysergamides
(lysergic acid amides)
Ergopeptines
(peptide ergolines)
Partial ergolines
Related compounds
Natural sources


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