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ALVAC-CEA vaccine

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Cancer vaccine

ALVAC-CEA vaccine is acancer vaccine containing acanary pox virus (ALVAC) combined with thecarcinoembryonic antigen (CEA)human gene.^[1]

A phase I trial in 118 patients showed safety in humans.^[2]

^"NCI Drug Dictionary".Comprehensive Cancer Information. Retrieved2024-07-02.
^Kaufman, Howard L.; Lenz, Heinz-Josef; Marshall, John; Singh, Deepti; Garett, Chris; Cripps, Christine; Moore, Malcolm; von Mehren, Margaret; Dalfen, Richard; Heim, William J.; Conry, Robert M.; Urba, Walter J.; Benson, Al B.; Yu, Maria; Caterini, Judy; Kim-Schulze, Seunghee; Debenedette, Mark; Salha, Danielle; Vogel, Thorsten; Elias, Ileana; Berinstein, Neil L. (2008)."Combination Chemotherapy and ALVAC-CEA/B7.1 Vaccine in Patients with Metastatic Colorectal Cancer".Clinical Cancer Research.14 (15):4843–4849.doi:10.1158/1078-0432.CCR-08-0276.PMID 18676757.S2CID 18152383.

Development

Classes

Administration

Vaccines

Bacterial	Anthrax Brucellosis Cholera^# Diphtheria^# Hib^# Leptospirosis Lyme disease^‡ Meningococcus^# MeNZB NmVac4-A/C/Y/W-135 Pertussis^# Plague Pneumococcal^# PCV PPSV Q fever Tetanus^# Tuberculosis BCG^# Typhoid^# Ty21a ViCPS Typhus combination: DPT/DTwP/DTaP Td/Tdap research: Clostridioides difficile Group B streptococcal disease Shigellosis
Viral	Adenovirus Chikungunya Ebola rVSV-ZEBOV Flu^# H1N1 (Pandemrix) H5N1 H5N8 LAIV Hantavirus Hepatitis A^# Hepatitis B^# Hepatitis E HPV^# Cervarix Gardasil Japanese encephalitis^# Measles^# Mpox Mumps^# Polio^# Sabin Salk Rabies^# Rotavirus^# Rubella^# SARS-CoV-2 Corbevax^† Bharat Biotech^† CanSino^† CoronaVac^† EpiVacCorona^† Janssen Kostaive Moderna Novavax Oxford–AstraZeneca Pfizer–BioNTech Sanofi–GSK^† Sinopharm BIBP^† Skycovione^† Sputnik V^† Valneva^† Respiratory syncytial virus (RSV) Smallpox Tick-borne encephalitis^# Varicella zoster Chicken pox^# Shingles Yellow fever^# combination: Hepatitis A and B MMR MMRV research: Cytomegalovirus Dengue^# Epstein–Barr virus Hepatitis C Herpes simplex HIV Zika
Protozoan	Malaria RTS,S research: Trypanosomiasis
Helminthiasis	research: Hookworm Schistosomiasis
Other	Androvax (androstenedione albumin) Cancer vaccines ALVAC-CEA BCG^# Hepatitis B^# HPV^# Cervarix Gardasil Prostvac NicVAX Ovandrotone albumin (Fecundin) TA-CD TA-NIC combination: DTaP-IPV/Hib DTaP-IPV-HepB DTwP-HepB-Hib Hexavalent vaccine

Inventors/
researchers

Controversy

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