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9α-Fluorocortisone

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
9α-Fluorocortisone
Clinical data
Other namesFluorocortisone; Alfluorone; 9α-Fluoro-17α,21-dihydroxypregn-4-ene-3,11,20-trione
Drug classCorticosteroid;Glucocorticoid
Identifiers
  • (8S,9R,10S,13S,14S,17R)-9-Fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
CAS Number
PubChemCID
ChemSpider
UNII
Chemical and physical data
FormulaC21H27FO5
Molar mass378.440 g·mol−1
3D model (JSmol)
  • C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2(C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)F
  • InChI=1S/C21H27FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-15,23,27H,3-8,10-11H2,1-2H3/t14-,15-,18-,19-,20-,21-/m0/s1
  • Key:BHDHELFREODRJK-XRYUJSLGSA-N

9α-Fluorocortisone, also known asalfluorone, is asyntheticglucocorticoidcorticosteroid which was never marketed.[1]

References

[edit]
  1. ^Elks J (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 565–566.ISBN 978-1-4757-2085-3.


GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others


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