 | |
| Clinical data | |
|---|---|
| Other names | 5α-DHNED; 4,5α-Dihydronorethandrolone; 3-Keto-5α-dihydroethylestrenol; 17α-Ethyl-5α-dihydro-19-nortestosterone; 17α-Ethyl-5α-estran-17β-ol-3-one; 19-Nor-5α-pregnan-17α-ol-3-one |
| Identifiers | |
| |
| CAS Number | |
| PubChemCID | |
| ChemSpider | |
| UNII | |
| CompTox Dashboard(EPA) | |
| Chemical and physical data | |
| Formula | C20H32O2 |
| Molar mass | 304.474 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
5α-Dihydronorethandrolone (5α-DHNED), also known as17α-ethyl-4,5α-dihydro-19-nortestosterone or as17α-ethyl-5α-estran-17β-ol-3-one, is anandrogen/anabolic steroid and ametabolite ofnorethandrolone (as well as of theprodrugethylestrenol) formed by5α-reductase.[1] Analogously tonandrolone and its 5α-reduced metabolite5α-dihydronandrolone, 5α-DHNED shows reducedaffinity for theandrogen receptor relative to norethandrolone.[1] Its affinity for the androgen receptor is specifically about 64% of that of norethandrolone.[1]
| Compound | rAR(%) | hAR(%) | ||||||
|---|---|---|---|---|---|---|---|---|
| Testosterone | 38 | 38 | ||||||
| 5α-Dihydrotestosterone | 77 | 100 | ||||||
| Nandrolone | 75 | 92 | ||||||
| 5α-Dihydronandrolone | 35 | 50 | ||||||
| Ethylestrenol | ND | 2 | ||||||
| Norethandrolone | ND | 22 | ||||||
| 5α-Dihydronorethandrolone | ND | 14 | ||||||
| Metribolone | 100 | 110 | ||||||
| Sources: See template. | ||||||||
